mirabegron

Known as: 2-(2-Aminothiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl] Acetamide, 4-Thiazoleacetamide, 2-Amino-N-(4-(2-(((2R)-2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)-, Betmiga 
An orally bioavailable agonist of the human beta-3 adrenergic receptor (ADRB3), with muscle relaxing, neuroprotective and potential antineoplastic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Increasing energy expenditure through activation of endogenous brown adipose tissue (BAT) is a potential approach to treat… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Combining the β3-adrenoceptor agonist mirabegron and the antimuscarinic (AM) agent solifenacin may improve efficacy in… (More)
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2014
2014
OBJECTIVE To evaluate the efficacy and safety of the β3-adrenoceptor agonist mirabegron, in a Japanese population with overactive… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Mirabegron, a β(3)-adrenoceptor agonist, has been developed for the treatment of overactive bladder (OAB). OBJECTIVE… (More)
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Highly Cited
2013
Highly Cited
2013
OBJECTIVE To assess the efficacy and tolerability of mirabegron 25 mg and 50 mg once-daily vs placebo in patients with overactive… (More)
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Highly Cited
2013
Highly Cited
2013
PURPOSE Many patients with overactive bladder discontinue pharmacotherapy due to suboptimal efficacy or side effects. Mirabegron… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Despite several antimuscarinic treatment options for overactive bladder (OAB), there is still a need for distinct… (More)
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Highly Cited
2013
Highly Cited
2013
INTRODUCTION To examine pooled efficacy data from three, large phase III studies comparing mirabegron (50 and 100 mg) with… (More)
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2013
2013
PURPOSE Bladder outlet obstruction often presents as storage and voiding symptoms. We investigated urodynamic parameters in men… (More)
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2012
2012
Overactive bladder (OAB) syndrome is defined as urinary urgency, usually accompanied by frequency and nocturia, with or without… (More)
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