microphthalmia-associated transcription factor

Known as: Microphthalmia Associated Transcription Factor, bHLHe32, Class E Basic Helix-Loop-Helix Protein 32 
A basic helix-loop-helix leucine zipper transcription factor that regulates the CELL DIFFERENTIATION and development of a variety of cell types… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Lysosomes are the major cellular site for clearance of defective organelles and digestion of internalized material. Demand on… (More)
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Highly Cited
2008
Highly Cited
2008
The origin of tumor heterogeneity is poorly understood, yet it represents a major barrier to effective therapy. In melanoma and… (More)
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Highly Cited
2008
Highly Cited
2008
Micropthalmia-associated transcription factor (MITF) is the master regulator of melanocyte development, survival, and function… (More)
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Highly Cited
2005
Highly Cited
2005
Systematic analyses of cancer genomes promise to unveil patterns of genetic alterations linked to the genesis and spread of human… (More)
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Review
2003
Review
2003
Microphthalmia-associated transcription factor (MITF) contains a basic helix-loop-helix and leucine-zipper (bHLH-LZ) structure… (More)
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Highly Cited
2002
Highly Cited
2002
Wnt signals regulate differentiation of neural crest cells through the beta-catenin associated with a nuclear mediator of the… (More)
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Highly Cited
2002
Highly Cited
2002
The transcription factor Microphthalmia-associated transcription factor (MITF) is a lineage-determination factor, which modulates… (More)
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Highly Cited
2000
Highly Cited
2000
Microphthalmia-associated transcription factor (Mitf) plays a critical role in the development of neural crest-derived… (More)
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Highly Cited
1997
Highly Cited
1997
Tyrosinase, tyrosinase-related protein-1 (TRP-1), and TRP-2 are the enzymes involved in melanin biosynthesis and are… (More)
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Highly Cited
1994
Highly Cited
1994
Tyrosinase is a rate-limiting enzyme in melanin biosynthesis and is specifically expressed in differentiated melanocytes. We have… (More)
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