methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity

Known as: 5,10-methylene-THF dehydrogenase activity, N5,N10-methylenetetrahydrofolate dehydrogenase activity

Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+. [EC:1.5.1.-, EC:1.5.1.15]

National Institutes of Health

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