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methylbenzoprim

Known as: 2,4-Pyrimidinediamine, 6-ethyl-5-(4-(methyl(phenylmethyl)amino)-3-nitrophenyl)- 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
  • G. J. Yoshida
  • Journal of Hematology & Oncology
  • 2017
  • Corpus ID: 4819768
The 2016 Nobel Prize in Physiology or Medicine was awarded to the researcher that discovered autophagy, which is an evolutionally… 
2016
2016
BackgroundThe antimalarial drug Pyrimethamine has been suggested to exert an antitumor activity by inducing apoptotic cell death… 
2004
2004
Benzimidazole-N-oxide modifications of potent lipophilic dihydrofolate reductase (DHFR) inhibitors (e.g., methylbenzoprim 1 and… 
2001
2001
Dichlorobenzoprim and methylbenzoprim were the lead compounds to emerge from investigations on a series of lipophilic 2,4-diamino… 
1997
1997
Twelve novel 2,4-diamino-5-(4'-benzylamino)- and 2,4-diamino-5[4'-(N-methylbenzylamino)-3'-nitrophenyl]-6-ethylp yrimidines… 
1992
1992
Methylbenzoprim (MBP) is a potent inhibitor of dihydrofolate reductase, which is more selective for mammalian than bacterial… 
1992
1992
Methylbenzoprim and ethylbenzoprim undergo debenzylation in hydrochloric acid. Two reaction mechanisms are proposed to explain… 
1990
1990
1H and 19F NMR signals from bound ligands have been assigned in one- and two-dimensional NMR spectra of complexes of… 
1990
1990
The new lipophilic dihydrofolate reductase inhibitor methylbenzoprim is a flexible substituted 2,4-diamino-5-arylpyrimidine…