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National Institutes of Health
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Pharmacokinetics, biodistribution and toxicology following intravenous and oral administration of DSM‐RX78 and EFB‐1, two new 2‐(2‐fluorobenzamido)benzoate‐based PDE4 inhibitors, to rats
The Journal of pharmacy and pharmacology
Corpus ID: 31092470
The aim of this study was to determine the pharmacokinetic profile, biodistribution and toxicity of ethyl 2‐(2‐fluorobenzamido…
DSM-RX78, a new phosphodiesterase inhibitor, suppresses superoxide anion production in activated human neutrophils and attenuates hemorrhagic shock-induced lung injury in rats.
Corpus ID: 5295036
Neutrophils are activated following hemorrhagic shock and the accumulation of neutrophils in the lung is associated with lung…
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