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methsuximide

Known as: N,2-dimethyl-2-phenylsuccinimide, Succinimide, N,2-dimethyl-2-phenyl-, Mesuximida 
A succinimide with anticonvulsant properties. Although the exact mechanism of action of methsuximide is unclear, it is thought to increase the… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (2)

AnticonvulsantsSuccinimides
Antiepileptic AgentsChildhood Absence EpilepsyDrug AllergyEpilepsy

Narrower (2)

CelontinNormethsuximide

Papers overview

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2000
2000
The amino terminus of PKA catalytic subunit—A site for introduction of posttranslation heterogeneities by deamidation: D‐Asp2 and D‐isoAsp2 containing isozymes
Conserved deamidation of PKA catalytic subunit isozymes Cα and Cβ—more than 25% at Asn2 in vivo in both cases—has been shown to… 
Highly Cited
1989
Highly Cited
1989
Syntheses and applications of water‐soluble reactive polymers for purification and immobilization of biomolecules
Reactive polymers have been prepared by copolymeriz‐ing N‐isopropyl acrylamide (NIPAM) with N‐acryloxy‐succinimide (NASI) or… 
1987
1987
A rapid method for the evaluation of new antituberculous agents.
Fifty-one new synthetic compounds belonging to four different series, namely (1a) substituted aryl-4-(substituted phenyl… 
1983
1983
INHIBITION OF AMINO ACID TRANSMITTER RELEASE FROM RAT BRAIN SLICES BY PHENYTOIN AND RELATED ANTICONVULSANTS
1. The in vitro effects of the major non‐benzodiazepine anticonvulsants were studied upon potassium‐stimulated release of… 
Highly Cited
1979
Highly Cited
1979
Kinetics and metabolism of carbamazepine during combined antiepileptic drug therapy
The kinetics of carbamazepine using 15N‐carbamazepine were investigated in epileptic patients during combined anticonvulsant… 
1979
1979
Pharmacological Interactions of Mesuximide with Phenobarbital and Phenytoin in Hospitalized Epileptic Patients
Summary: In order to study the pharmacological interactions of the anticonvulsant drugs mesuximide (MSM), phenobarbital (PB), and… 
1973
1973
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
1973
1973
Methsuximide overdose. Delayed onset of profound coma.
  • S. Karch
  • Journal of the American Medical Association (JAMA…
  • 1973
  • Corpus ID: 34308589
To my knowledge, this is the third reported case of methsuximide overdosage. The resulting disorder is biphasic in nature, an… 
Highly Cited
1966
Highly Cited
1966
The estimation of some important anticonvulsant drugs in serum.
  • J. Huisman
  • Clinica chimica acta; international journal of…
  • 1966
  • Corpus ID: 38252453
Highly Cited
1962
Highly Cited
1962
Ethosuximide in the treatment of epilepsy.
THIS STUDY deals with the effectiveness of ethosuximide (Zarontin) in the treatment of 100 patients with recurrent, short, mild… 
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