methsuximide

Known as: N,2-Dimethyl-2-phenylsuccinimide, Succinimide, N,2-dimethyl-2-phenyl-, Mesuximida 
A succinimide with anticonvulsant properties. Although the exact mechanism of action of methsuximide is unclear, it is thought to increase the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
051019572017

Papers overview

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2001
2001
The authors investigated whether methsuximide affects serum levels of valproic acid. Pre-morning-dose serum valproic acid levels… (More)
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Highly Cited
2001
Highly Cited
2001
Inhibition of T-type Ca(2+) channels has been proposed to play a role in the therapeutic action of succinimide antiepileptic… (More)
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2000
2000
PURPOSE To determine whether methsuximide (MSM) affects lamotrigine (LTG) blood levels and whether any change is of clinical… (More)
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1999
1999
The aim of this retrospective study was to investigate the influence of oxcarbazepine (OCBZ) and methsuximide (MSM) on… (More)
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1996
1996
Currently valproic acid is considered to be the drug of first choice for juvenile myoclonic epilepsy (JME) resulting in a 70-90… (More)
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1991
1991
Methsuximide was added to the therapeutic regimens of 25 children with intractable epilepsy. In 15 patients the drug was well… (More)
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1987
1987
Learning impairment is a potentially serious side effect of antiepilepsy medications. The present study investigated the effects… (More)
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1983
1983
Methsuximide (MSM; Celontin) was administered for 8 weeks to 26 patients with complex partial seizures (CPS) refractory to… (More)
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1981
1981
The efficacy and safety of methsuximide were evaluated for 12 weeks in 21 patients with complex partial (psychomotor) seizures… (More)
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1977
1977
Interictal spikes with a configuration similar to that occurring in grand mal epilepsy were generated by the application of… (More)
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