methotrexate transport

The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2014
024619742014

Papers overview

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2004
2004
Human organic anion transporters hOAT1 (SLC22A6) and hOAT3 (SLC22A8) are responsible for renal tubular secretion of an antifolic… (More)
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2003
2003
Overexpression of the ATP-binding cassette transporter ABCG2 reportedly causes multidrug resistance, whereas altered drug… (More)
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Highly Cited
2002
Highly Cited
2002
Life-threatening drug interactions are known to occur between methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs… (More)
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2001
2001
The ATP-binding cassette (ABC) proteins comprise a large superfamily of transmembrane transporters that utilize the energy of ATP… (More)
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1999
1999
Renal organic anion transporter OAT-K1 was stably transfected in MDCK cells and examined for its transport characteristics and… (More)
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1995
1995
This report describes the isolation, nucleotide sequencing, and functional expression of human cDNAs that restore reduced folate… (More)
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1990
1990
This study reports the isolation and characterization of a variant of the human CCRF-CEM leukemia cell line that overproduces the… (More)
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1987
1987
We have studied the frequency of transport mutations in methotrexate-resistant Chinese hamster ovary cells using a rapid-flow… (More)
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1983
1983
Methotrexate transport parameters have been compared in L1210 cells suspended in a series of HEPES buffer systems of varying… (More)
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1976
1976
Net accumulation of methotrexate by carrier-mediated transport in different murine tumor cells in vitro exhibits a positive… (More)
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