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methotrexate transport

The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Human organic anion transporters hOAT1 (SLC22A6) and hOAT3 (SLC22A8) are responsible for renal tubular secretion of an antifolic… 
Highly Cited
2003
Highly Cited
2003
Overexpression of the ATP-binding cassette transporter ABCG2 reportedly causes multidrug resistance, whereas altered drug… 
Highly Cited
2002
Highly Cited
2002
Life-threatening drug interactions are known to occur between methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs… 
Highly Cited
2001
Highly Cited
1995
Highly Cited
1995
A retrospective study of clinical resistance to methotrexate (MTX) was performed on 29 archival specimens of frozen lymphoblasts… 
Highly Cited
1995
Highly Cited
1995
This report describes the isolation, nucleotide sequencing, and functional expression of human cDNAs that restore reduced folate… 
Highly Cited
1987
Highly Cited
1987
We have studied the frequency of transport mutations in methotrexate-resistant Chinese hamster ovary cells using a rapid-flow… 
Highly Cited
1985
Highly Cited
1985
A human T-lymphoblast cell line, CCRF-CEM/R1, resistant to methotrexate by virtue of increased dihydrofolate reductase activity…