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methionine sulfoxide (protein) reductase activity

Known as: peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity, methionine S-oxide reductase (S-form oxidizing) activity, peptide-methionine-(S)-S-oxide reductase activity 
Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new… Expand
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Highly Cited
2009
Highly Cited
2009
To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide… Expand
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Review
2009
Review
2009
Methionine sulfoxide reductases (Msrs) are thiol-dependent enzymes which catalyze conversion of methionine sulfoxide to… Expand
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Highly Cited
2007
Highly Cited
2007
The reduction of methionine sulfoxide (MetO) is mediated by methionine sulfoxide reductases (Msr). The MsrA and MsrB families can… Expand
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Review
2005
Review
2005
Atherosclerosis is still an important disease. It accounts for 39% of deaths in the U.K. and 12 million U.S citizens have… Expand
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Highly Cited
2004
Highly Cited
2004
Age-related cataract, an opacity of the eye lens, is the leading cause of visual impairment in the elderly, the etiology of which… Expand
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Highly Cited
2001
Highly Cited
2001
Oxidation of proteins by reactive oxygen species is associated with aging, oxidative stress, and many diseases. Although free and… Expand
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Highly Cited
2001
Highly Cited
2001
Inducible nitric oxide synthase (iNOS) plays an important role in host defense. Macrophages expressing iNOS release the reactive… Expand
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Highly Cited
1999
Highly Cited
1999
Previous studies have shown that the pathophysiology of Alzheimer's disease (AD) is linked to oxidative stress. Oxidative damage… Expand
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Highly Cited
1997
Highly Cited
1997
A gene homologous to methionine sulfoxide reductase (msrA) was identified as the predicted ORF (cosmid 9379) in chromosome V of… Expand
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