methionine sulfoxide (protein) reductase activity

Known as: peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity, methionine S-oxide reductase (S-form oxidizing) activity, peptide-methionine-(S)-S-oxide reductase activity 
Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine… (More)
National Institutes of Health

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Topic mentions per year

1970-2017
0102019702017

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Highly Cited
2010
Highly Cited
2010
Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new… (More)
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2010
2010
Mg(2+) is an essential ion for many cellular processes, including protein synthesis, nucleic acid stability, and numerous… (More)
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2009
2009
Protein oxidation has been linked to accelerated aging and is a contributing factor to many diseases. Methionine residues are… (More)
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2008
2008
Methionine (Met) residues are present in most proteins. However, this sulfur-containing amino acid is highly susceptible to… (More)
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2007
2007
One of the posttranslational modifications to proteins is methionine oxidation, which is readily reversible by the methionine… (More)
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Highly Cited
2004
Highly Cited
2004
Aging is thought to be caused by the accumulation of damage, primarily from oxidative modifications of cellular components by… (More)
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2003
2003
Mammals contain two methionine sulfoxide (MetO) reductases, MsrA and MsrB, that catalyze the thioredoxin-dependent reduction of… (More)
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Highly Cited
2001
Highly Cited
2001
Oxidation of proteins by reactive oxygen species is associated with aging, oxidative stress, and many diseases. Although free and… (More)
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Highly Cited
2001
Highly Cited
2001
Inducible nitric oxide synthase (iNOS) plays an important role in host defense. Macrophages expressing iNOS release the reactive… (More)
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Highly Cited
1997
Highly Cited
1997
A gene homologous to methionine sulfoxide reductase (msrA) was identified as the predicted ORF (cosmid 9379) in chromosome V of… (More)
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