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methacholine challenge

Known as: challenge methacholine 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Regional pulmonary response to a methacholine challenge using hyperpolarized 3He magnetic resonance imaging
Background and objective:  Spirometry is insensitive to small airway abnormalities in asthma. Our objective was to evaluate… 
2009
2009
Hospital admission for acute painful episode following methacholine challenge in an adolescent with sickle cell disease
Asthma is associated with increases in sickle cell disease (SCD)‐related morbidity and mortality. A thorough evaluation for… 
Review
2009
Review
2009
The FEF25–75 and its Decline as a Predictor of Methacholine Responsiveness in Children
Background. Methacholine challenge (MCC) is an important diagnostic tool for asthma, especially in patients in whom routine… 
Highly Cited
2007
Highly Cited
2007
Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma.
RATIONALE Exhaled breath nitric oxide (Fe(NO)) is increased in asthma. NO is produced predominantly by inducible nitric oxide… 
2002
2002
Lower airway inflammatory responses to repeated very‐low‐dose allergen challenge in allergic rhinitis and asthma
  • M. Boulay, L. Boulet
  • Clinical and experimental allergy : journal of…
  • 2002
  • Corpus ID: 20306223
Background Low‐dose allergen challenge (LDAC) may be a useful tool for studying the capacity of allergens to induce airway… 
Highly Cited
2000
Highly Cited
2000
The effect of inhaled budesonide on symptoms, lung function, and cold air and methacholine responsiveness in 2- to 5-year-old asthmatic children.
We hypothesized that measurement of lung function (LF) and bronchial hyperresponsiveness (BHR) could serve as supplemental tools… 
Highly Cited
1998
Highly Cited
1998
Relation between occupational asthma case history, bronchial methacholine challenge, and specific challenge test in patients with suspected occupational asthma.
Inhalative methacholine challenge (MC) was performed in 229 subjects presumed to suffer from occupational asthma due to exposure… 
Review
1996
Review
1996
Prior diagnosis and treatment of patients with normal results of methacholine challenge and unexplained respiratory symptoms.
OBJECTIVE Previous research indicates that asthma has been underdiagnosed. However, we suspect that recent widespread attention… 
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Highly Cited
1993
Highly Cited
1993
Wheezing and airflow obstruction during methacholine challenge in children with cystic fibrosis and in normal children.
To study wheeze as an indicator of bronchial responses during standardized methacholine challenge (MCH), we used computerized… 
1993
1993
Acoustic vs. spirometric assessment of bronchial responsiveness to methacholine in children.
To study wheezing as an indicator of bronchial responsiveness during methacholine challenge (MC) in children, we used computer… 
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