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G-protein-coupled receptors (GPCRs) are seven transmembrane helix (TM) proteins that transduce signals into living cells by… Expand Arrestin blocks the interaction of rhodopsin with the G protein transducin (Gt). To characterize the sites of arrestin that… Expand In order to investigate the molecular mechanism of rhodopsin photoactivation, site-directed mutants of bovine rhodopsin were… Expand A prevalent model for the function of rhodopsin centers on the metarhodopsin I (MI) to metarhodopsin II (MII) conformational… Expand A method was developed to measure Fourier-transform infrared (FTIR) difference spectra of detergent-solubilized rhodopsin… Expand The biologically active photoproduct of rhodopsin, metarhodopsin II (M II), exists in a pH-sensitive equilibrium with its… Expand The effect of lipid ordering on the kinetics and extent of metarhodopsin II (meta II) formation was evaluated in bovine rhodopsin… Expand We have found that the 48-kDa protein (or S-antigen 48k) of the rod photoreceptor enhances the light-induced formation of the… Expand We have previously described [H, Kühn et al. (1981) Proc. Natl Acad. Sci. USA, 78, 6873-6877] a light-induced scattering change… Expand The resonance Raman spectra of bovine metarhodopsin I and metarhodopsin II have been measured. The spectra are compared with… Expand