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mesulergine

Known as: N'-(1,6-dimethylergolin-8alpha-yl)-N,N-dimethylsulfamide 
 
National Institutes of Health

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Related topics

4 relations

Broader (4)

Antiparkinson AgentsDopamine AgonistsErgolinesSerotonin Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Autoradiographic distribution of 5-HT7 receptors in the human brain using [3H]mesulergine: comparison to other mammalian species.
1. The main aim of this investigation was to delineate the distribution of the 5-HT(7) receptor in human brain. Autoradiographic… Expand
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Highly Cited
2004
Highly Cited
2004
8-OH-DPAT as a 5-HT7 agonist: phase shifts of the circadian biological clock through increases in cAMP production
Neurons in the suprachiasmatic nucleus (SCN), the site of the endogenous biological clock in mammals, fire spontaneously, peaking… Expand
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Highly Cited
2000
Highly Cited
2000
Serotonin receptor subtypes involved in the spinal antinociceptive effect of 5-HT in rats
The present study was designed to investigate which subtypes of spinal 5-HT receptors are involved in 5-HT-induced… Expand
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Highly Cited
1995
Highly Cited
1995
(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and…
In this study, the involvement of serotonergic and dopaminergic receptors in the modulation of the head-twitch (HTW) response to… Expand
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Highly Cited
1993
Highly Cited
1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Serotonin modulates a wide range of physiological functions by activating multiple receptors, which are coupled to various… Expand
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Highly Cited
1992
Highly Cited
1992
Serotonin is a directly-acting hyperalgesic agent in the rat
In this study, we have investigated serotonin hyperalgesia employing the mechanical paw withdrawal nociceptive threshold test in… Expand
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Highly Cited
1988
Highly Cited
1988
A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system.
A nonclassical 5-hydroxytryptamine (5-HT) receptor mediates the stimulation of adenylate cyclase activity in mouse embryo… Expand
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Highly Cited
1988
Highly Cited
1988
Evidence that mCPP may have behavioural effects mediated by central 5-HT1C receptors.
1. The effects of 1-(3-chlorophenyl)piperazine (mCPP) and 1-[3-(trifluoromethyl)phenyl] piperazine (TFMPP) on activity of rats in… Expand
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Highly Cited
1985
Highly Cited
1985
Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and…
The pharmacological characteristics of the binding of [3H]8-OH-DPAT ([3H]8-hydroxy-2(di-n-propylamino)tetralin, [125I]CYP… Expand
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1984
1984
Mesulergine, a selective serotonin-2 ligand in the rat cortex, does not label these receptors in porcine and human cortex: evidence for species differences in brain serotonin-2 receptors.
The kinetic and pharmacological characteristics of the binding of [3H]ketanserin and [3H]mesulergine to frontal cortical brain… Expand
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