mesenchymal cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated… (More)
National Institutes of Health

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2013
2013
Human mesenchymal stem cells (hMSCs) can differentiate into various cell types, including osteogenic and chondrogenic cells. The… (More)
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Highly Cited
2010
Highly Cited
2010
Aging leads to the disruption of the homeostatic balance of multiple biological systems. In bone marrow multipotent mesenchymal… (More)
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Highly Cited
2008
Highly Cited
2008
Notch signaling is a key mechanism in the control of embryogenesis. However, its in vivo function during mesenchymal cell… (More)
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Highly Cited
2007
Highly Cited
2007
A key tenet of bone tissue engineering is the development of scaffold materials that can stimulate stem cell differentiation in… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The two most basic properties of mesenchymal stem cells (MSCs) are the capacities to self-renew indefinitely and… (More)
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2005
2005
UNLABELLED Runx proteins mediate skeletal development. We studied the regulation of Runx1 during chondrocyte differentiation by… (More)
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2003
2003
Cytokines, such as tumor necrosis factor-alpha (TNFalpha), potently inhibit the differentiation of mesenchymal cells and down… (More)
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2003
Highly Cited
2003
During tooth development, after the completion of crown formation, the apical mesenchyme forms the developing periodontium while… (More)
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2002
Highly Cited
2002
Preclinical and clinical studies suggest a possible role for cyclooxygenases in bone repair and create concerns about the use of… (More)
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2000
2000
The pluripotent mesenchymal stem cells give rise to osteoblasts, adipocytes, chondrocytes, and myoblasts. The differentiation of… (More)
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