mericitabine

Known as: 2' alpha-fluoro-2' beta-methyl-3',5'-diisobutyryldeoxycytidine, 2'-deoxy-2'-fluoro-2'-c-methylcytidine Diisobutyrate, 3',5'-diisobutyryl PSI 6130 
An orally available prodrug of PSI-6130 which is a selective cytidine nucleoside analogue and non-cytotoxic hepatitis C virus (HCV) polymerase… (More)

Topic mentions per year

Topic mentions per year

2012-2016
051020122016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
BACKGROUND & AIMS Safety and tolerability of peginterferon-based hepatitis C virus (HCV) infection therapy remains suboptimal… (More)
Is this relevant?
2014
2014
BACKGROUND Resistance to mericitabine (prodrug of HCV NS5B polymerase inhibitor PSI-6130) is rare and conferred by the NS5B S282T… (More)
Is this relevant?
2014
2014
The direct-acting antivirals (DAAs) currently in development for treatment of hepatitis C fall into four categories: (i) NS3/4A… (More)
Is this relevant?
2014
2014
UNLABELLED Hepatitis C virus (HCV) is a genetically diverse virus with multiple genotypes exhibiting remarkable differences… (More)
  • figure 1
  • table 3
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2014
2014
Baseline and posttreatment samples from hepatitis C virus (HCV) genotype (GT) 1-infected patients who received a combination of… (More)
Is this relevant?
2013
2013
UNLABELLED Mericitabine is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2013
2013
UNLABELLED Mericitabine is a nucleoside analog polymerase inhibitor of hepatitis C virus (HCV). Treatment-naïve HCV genotype 1 or… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2012
2012
UNLABELLED Mericitabine (RG7128) is a nucleoside polymerase inhibitor (NPI), which requires intracellular uptake and… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
Is this relevant?
2012
2012
In the INFORM-1 study, 73 patients with chronic hepatitis C virus infection received mericitabine plus danoprevir for up to 13… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
2012
2012
BACKGROUND & AIMS Although interleukin 28B (interferon, lambda 3) (IL28B) genotype affects the response of patients with chronic… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?