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mepitiostane

Known as: 2-alpha,3 alpha-epithio-5 alpha-androstan-17 beta-yl-1-methoxycyclopentyl ether, androstane, 2,3-epithio-17-((1-methoxycyclopentyl)oxy)-, (2 alpha,3 alpha,5 alpha,17 beta)- 
An anabolic ether-modified form of the steroid epitiostanol. It has anti-estrogenic effect, which inhibits the progression of estrogen-stimulated… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (1)

10364-S

Broader (4)

Anabolic AgentsAndrostanolsAntineoplastic AgentsEstrogen Antagonists

Papers overview

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2000
2000
[1a(1a alpha,5 beta,9a alpha)]-1,1a,4,5,7,8,9,9a-Octahydro-3-hydroxy-1,1,2,5- tetramethyl-7-methylene-6H-cyclopropa-[3,4]cyclohept[1,2-e] inden-6-one.
1990
1990
Successful treatment of a patient with posthepatitic severe aplastic anemia with bolus methylprednisolone.
A 31-year-old female developed severe aplastic anemia following acute non-A non-B hepatitis. Because of the impossibility of bone… 
Review
1989
Review
1989
[Complete remission by mepitiostane in hypoplastic leukemia].
A 71-year-old female was diagnosed as hypoplastic leukemia (ALL, L 2). Vitamin D3 (D3) therapy with alfacalcidol was successful… 
1989
1989
A case of hybrid phenotypic chronic myelomonocytic leukemia transformed from aplastic anemia.
A case of hybrid phenotypic chronic myelomonocytic leukemia (CMMoL) transformed from a hematological remission state of severe… 
1987
1987
Synthesis and antiviral evaluation of carbocyclic analogues of 2-amino-6-substituted-purine 3'-deoxyribofuranosides.
Carbocyclic analogues of 2-amino-6-substituted-purine 3'-deoxyribofuranosides were synthesized by beginning with (+/-)-(1 alpha,3… 
1985
1985
A phase III trial of oral high‐dose medroxyprogesterone acetate (MPA) versus mepitiostane in advanced postmenopausal breast cancer
A randomized controlled trial was performed to compare the therapeutic results of oral high‐dose medroxyprogesterone acetate (HD… 
1985
1985
[Clinical investigation of oral high-dose medroxyprogesterone acetate (MPA) in advanced breast cancer--double-blind controlled study: Japanese Group for MPA Treatment of Breast Cancer].
A randomized controlled trial was made to compare the therapeutic result of oral high-dose medroxyprogesterone acetate (HD-MPA… 
1980
1980
Adjuvant endocrine therapy for operable breast cancer using the antiestrogen mepitiostane: a preliminary report.
The steroidal antiestrogen, mepitiostane (Thioderone, 2 alpha, 3 alpha-epitio-5 alpha-androstane-17 beta-yl 1-methoxycyclopentyl… 
1978
1978
Therapeutic value of mepitiostane in the treatment of advanced breast cancer.
A new, orally active antiestrogenic steroid, mepitiostane (20 mg/day), was given to 45 patients with advanced breast cancer. The… 
1976
1976
Hepatic 15-hydroxylation of corticosteroids in the rat. Substrate specificity studied in the isolated perfused liver.
The substrate specificity of a sex-specific hepatic 15-hydroxylase active on different C21O2 and C21O3 steroids was studied in… 
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