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mepiprazole

 
National Institutes of Health

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Piperazines

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1983
1983
Evidence that blood pressure reduction by serotonin antagonists is related to alpha receptor blockade in spontaneously hypertensive rats.
In vitro affinity for vascular 5HT2 and alpha receptors was determined for several compounds (spiperone, ketanserin, mianserin… Expand
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1982
1982
1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole.
 
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1981
1981
Structure-activity relationships in the actions of 1-phenyl-piperazines on brain serotonin receptors.
Several compounds containing a 1-phenyl-piperazine moiety have been reported to interact with central serotoninergic systems. For… Expand
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1980
1980
Central action of mepiprazole.
Mepiprazole, a phenylpiperazine derivative, strongly antagonizes the behavioral syndromes evolved by 5-hydroxytrypotophan. The… Expand
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1976
1976
Mepiprazole, a new psychotropic drug: Effects on uptake and retention of monoamines in rat brain synaptosomes
The influence of mepiprazole (EMD 16,923), a new pyrazol-ylalkyl-piperazine derivative, on the uptake of 3H-norepinephrine (NE… Expand
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1976
1976
Effects of time zone changes on performance and physiology of airline personnel.
 
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1976
1976
The effect of mepiprazole on central monoamine neurons. Evidence for increased 5-hydroxytryptamine and dopamine receptor activity.
In combined biochemical, histochemical and functional studies on central monoamine neurons it has been shown that a pyrozolyl… Expand
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1976
1976
Effects of time zone changes on performance and physiology of airline personnel.
This study is the second of a series of experiments describing the effects of time zone changes on the performance and menstrual… Expand
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1976
1976
[The influence of mepiprazol on monoamine metabolism in the rat CNS: demonstration of reduced norepinephrine activity and simultaneously enhanced serotonin and dopamine activities (author's transl)].
Biochemical studies of monamine turnover and neuronal reuptake indicate that mepiprazole, a novel psychotropic pyrazole… Expand
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1974
1974
Controlled clinical trial of mepiprazole in irritable bowel syndrome.
The effect of a new tranquillizer, mepiprazole, in the treatment of the irritable bowel syndrome has been studied in a double… Expand
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