FAQ

melarsen

Known as: N-(4,6-diamino-s-triazin-2-yl)arsanilic acid disodium salt 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2013
0119572013

Related topics

Related topics

1 relation

Broader (1)

Arsenicals

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
melarsen
Arsenicals

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Determination of the trypanocidal drug melarsoprol and its conversion products in biological fluids with HPLC-ICPMS/ESMS.
Although melarsoprol, an organoarsenic compound, is widely used for the treatment of trypanosomiasis (human African sleeping… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
2001
2001
Identification and characterization of trypanocides by functional expression of an adenosine transporter from Trypanosoma brucei in yeast
The causative agents of sleeping sickness, Trypanosoma brucei rhodesiense and T. brucei gambiense, do not synthesize purines de… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei.
The African trypanosome, Trypanosoma brucei brucei, possesses at least two nucleoside transporter systems designated P1 and P2… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Arsenical-resistant trypanosomes lack an unusual adenosine transporter
THE melaminophenyl arsenical melarsoprol is still used to treat African sleeping sickness1–3, a disease caused by parasitic… (More)
Is this relevant?
1992
1992
Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism.
An arsenical resistant cloned line of Trypanosoma brucei brucei was derived from a parent sensitive clone by repeated selection… (More)
Is this relevant?
1974
1974
Susceptibility of an insect Leptomonas and Crithidia fasciculata to several established antitrypanosomatid agents.
Growth inhibition of the lower trypanosomatids Crithidia fasciculata and a Leptomonas from a hemipteron by several established… (More)
  • table 2
  • table 3
  • table 4
Is this relevant?
1971
1971
Diagnosis of Gambian trypanosomiasis in man by isolating trypanosomes from blood passed through DEAE-cellulose.
A method is described whereby small numbers of trypanosomes in blood can be concentrated free of blood cells on to a slide… (More)
Is this relevant?
1957
1957
Melarsen in the treatment of Trypanosoma gambiense infection in man.
 
Is this relevant?