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melarsen

Known as: N-(4,6-diamino-s-triazin-2-yl)arsanilic acid disodium salt 
 
National Institutes of Health

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Arsenicals

Papers overview

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2013
2013
Determination of the trypanocidal drug melarsoprol and its conversion products in biological fluids with HPLC-ICPMS/ESMS.
Although melarsoprol, an organoarsenic compound, is widely used for the treatment of trypanosomiasis (human African sleeping… Expand
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2001
2001
Identification and characterization of trypanocides by functional expression of an adenosine transporter from Trypanosoma brucei in yeast
The causative agents of sleeping sickness, Trypanosoma brucei rhodesiense and T. brucei gambiense, do not synthesize purines de… Expand
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1974
1974
Inhibition by several standard antiprotozoal drugs of growth and O2 uptake of cells and particulate preparations of a Leptomonas.
SYNOPSIS Drug sensitivities of a lower trypanosomatid, Leptomonas sp. from the hemipteran Dysdercus, to antitrypanosomatid… Expand
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1972
1972
[Routes and kinetics of arsenic elimination in rats after administration of organoarsenic drugs. 3. Study of amino-4-benzene arsenic acid and melarsen].
 
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1971
1971
Diagnosis of Gambian trypanosomiasis in man by isolating trypanosomes from blood passed through DEAE-cellulose.
A method is described whereby small numbers of trypanosomes in blood can be concentrated free of blood cells on to a slide… Expand
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1962
1962
Estimation of the concentration of melarsoprol (Mel B) and Mel W in biological fluids by bioassay with trypanosomes in vitro.
  • Frank Hawking
  • Transactions of the Royal Society of Tropical…
  • 1962
    • Corpus ID: 45011720
Abstract 1. 1) A technique for the bioassay of melarsoprol and similar compounds is described; it depends upon measuring the in… Expand
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1962
1962
Treatment of African Trypanosomiasis with Melarsen, Melarsen Oxide, Mel B and Mel W.
 
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1957
1957
Melarsen in the treatment of Trypanosoma gambiense infection in man.
Abstract 1. The results are given of further trials with melarsen in the treatment of cases of human sleeping sickness under… Expand
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1951
1951
The efficacy of certain trypanocidal compounds against Trypanosoma gambiense infection in man.
Abstract 1. (1) The results are given of trials with trypanocidal drugs in cases of human sleeping sickness in Northern Nigeria… Expand
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1949
1949
Estimation of Melarsen and Mel B in Blood and Urine.
 
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