melagatran

Known as: N-((R)-(((2S)-2-((-p-amidobenzyl)carbamoyl)-1-azetidinyl)carbonyl)cyclohexylmethyl)glycine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0204019972017

Papers overview

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2006
2006
OBJECTIVE Inflammatory mechanisms are involved in atherosclerotic plaque rupture and subsequent thrombin formation. Thrombin not… (More)
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2004
2004
The objectives were to investigate whether activation of the extrinsic coagulation cascade by recombinant factor VIIa (rFVIIa… (More)
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2003
2003
BACKGROUND Ximelagatran and its subcutaneous (s.c.) form melagatran are novel direct thrombin inhibitors for the prevention and… (More)
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Highly Cited
2002
Highly Cited
2002
A thrombotic/inflammatory reaction is elicited when isolated islets of Langerhans come in contact with ABO-compatible blood. The… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Heparins substantially reduce the risk of thromboembolic complications after total hip or knee replacement. However… (More)
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2002
2002
The novel, oral direct thrombin inhibitor, ximelagatran (formerly H 376/95), represents an advance in antithrombotic therapy… (More)
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Highly Cited
2001
Highly Cited
2001
UNLABELLED Suboptimal gastrointestinal absorption is a problem for many direct thrombin inhibitors. The studies presented herein… (More)
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2001
2001
Prothrombin time (PT) assays are clotting methods that measure the activity of vitamin K-dependent coagulation factors (F) II… (More)
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1999
1999
Forty-eight patients with acute proximal deep vein thrombosis (DVT) were randomised to intravenous infusions for 4 to 6 days with… (More)
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1998
1998
Melagatran, a new, competitive and rapid inhibitor of thrombin with a molecular mass of 429 Da is described. Melagatran is well… (More)
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