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medroxalol

Known as: 5-(2-((3-(1,3-benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)-2-hydroxybenzamide, benzamide, 5-(2-((3-(1,3-benzodioxol)-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl-2-hydroxy- 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Adrenergic alpha-AntagonistsAdrenergic beta-AntagonistsAntihypertensive AgentsEthanolamines

Narrower (1)

RMI 81968

Papers overview

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Review
2012
Review
2012
An Overview of the Pharmacodynamic Properties and Therapeutic Potential of Combined α- and β-Adrenoceptor Antagonists
SummaryHaemodynamically, the combination of α1- and β-adrenoceptor antagonists is a logical one. α1-Adrenoceptor blockade causes… 
1986
1986
Antihypertensive aminotetralins related to labetalol and medroxalol.
A series of compounds was prepared in which the 1-methyl-3-phenylpropylamino moieties of the antihypertensive agents labetalol… 
1984
1984
Analysis of the hypotensive effects of medroxalol and its enantiomers, MDL 17,330A and MDL 17,331A.
Medroxalol and two of its enantiomers (MDL 17, 330A , MDL 17, 331A ) were tested for activity at adrenergic receptors to clarify… 
1983
1983
Vasodilation by medroxalol mediated by beta 2-adrenergic receptor stimulation.
A contribution by active vasodilation to the hypotensive effect of medroxalol was investigated in anesthetized dogs and… 
1983
1983
Bioavailability of medroxalol in man.
Ten healthy male volunteers received single oral doses of 100 mg of medroxalol administered as a solution, a preliminary tablet… 
1983
1983
Kinetics of medroxalol, a beta- and alpha-adrenoceptor antagonist.
Eight healthy men received single oral doses of 400, 800, and 1200 mg medroxalol and a single intravenous dose of 1 mg per kg… 
1982
1982
β and α‐Adrenoceptor Antagonism by Medroxalol in Healthy Volunteers: Relationship to Dose and Plasma Concentration
Summary We studied β- and α-adrenoceptor blockades by medroxalol in eight normal, male volunteers using exercise and… 
1982
1982
Treatment of Mild and Moderate Hypertension with Medroxalol, an α and β‐Adrenergic Antagonist
Medroxalol, a new antihypertensive agent with α- and β-adrenoreceptor blocking properties in both animals and humans, was… 
1982
1982
Treatment of mild and moderate hypertension with medroxalol, an alpha- and beta-adrenergic antagonist.
Medroxalol, a new antihypertensive agent with alpha- and beta-adrenoreceptor blocking properties in both animals and humans, was… 
1981
1981
Salicylamide derivatives related to medroxalol with alpha- and beta-adrenergic antagonist and antihypertension activity.
Analogues of medroxalol (1) were prepared in which the carboxamide function, the phenolic hydroxy group, and the aralkylamine… 
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