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matrix metalloproteinase 12

Known as: Metalloproteinase, MMP12, Macrophage-Specific Metalloelastase, MMP12 Metalloproteinase 
A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Elastin has been linked to maturity of liver fibrosis. To date, the regulation of elastin secretion and its degradation in liver… Expand
Highly Cited
2004
Highly Cited
2004
ABSTRACT Background Chronic obstructive pulmonary disease and emphysema are a frequent result of long-term smoking, but the exact… Expand
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Highly Cited
2001
Highly Cited
2001
There is increasing evidence that antiproteases are able to affect the inflammatory response. To further examine this question… Expand
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE To determine molecular mechanisms involved in angiogenesis of hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA… Expand
Highly Cited
2000
Highly Cited
2000
Mouse macrophage metalloelastase (MME) has been associated with the generation of angiostatin, an internal fragment of… Expand
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Highly Cited
1999
Highly Cited
1999
Although the metalloproteinase murine metalloelastase (MME) has been implicated in lung disorders such as emphysema and pulmonary… Expand
Highly Cited
1997
Highly Cited
1997
The aim of this study was to examine the hypothesis that alveolar macrophages represent a significant source of matrix-degrading… Expand
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Highly Cited
1996
Highly Cited
1996
Macrophages secrete a variety of proteinases that are thought to participate in remodeling of the extracellular matrix associated… Expand
Highly Cited
1996
Highly Cited
1996
Several matrix metalloproteinases, including the 92-kDa and 72-kDa gelatinases, macrophage metalloelastase (MME), and matrilysin… Expand
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Highly Cited
1995
Highly Cited
1995
Human macrophage metalloelastase (HME) is a recent addition to the matrix metalloproteinase (MMP) family that was initially found… Expand