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matrix metalloproteinase 12

Known as: Metalloproteinase, MMP12, Macrophage-Specific Metalloelastase, MMP12 Metalloproteinase 
A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.
National Institutes of Health

Papers overview

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2015
2015
Interstitial fluid flow in and around the tumor tissue is a physiologically relevant mechanical signal that regulates… Expand
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2014
2014
Whereas cigarette smoking remains the main risk factor for emphysema, recent studies in β-epithelial Na(+) channel-transgenic… Expand
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2010
2010
OBJECTIVE Studies have shown that in systemic sclerosis (SSc) endothelial cells, overproduction of matrix metalloproteinase 12… Expand
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2009
2009
Chronic obstructive pulmonary disease (COPD) and lung cancer are two diseases that are related to smoking in humans. The… Expand
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2008
2008
OBJECTIVE Histone acetylation/deacetylation plays an important role in the control of gene expression, tissue growth, and… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Chronic obstructive pulmonary disease and emphysema are a frequent result of long-term smoking, but the exact… Expand
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2000
2000
Several members of the newly emerging astacin metalloproteinase family have been shown to function in a variety of biological… Expand
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Highly Cited
1998
Highly Cited
1997
Highly Cited
1997
The aim of this study was to examine the hypothesis that alveolar macrophages represent a significant source of matrix-degrading… Expand
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Highly Cited
1996
Highly Cited
1996
Macrophages secrete a variety of proteinases that are thought to participate in remodeling of the extracellular matrix associated… Expand
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