mast cell activation

The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
05010019732018

Papers overview

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Highly Cited
2008
Highly Cited
2008
Mast cells have key functions as effectors of immunoglobulin E–mediated allergic inflammatory diseases. Allergen stimulation… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Mast cells are major effector cells in allergy and host defense responses. Their increased number and state of… (More)
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Highly Cited
2006
Highly Cited
2006
Bronchial asthma, the most prevalent cause of significant respiratory morbidity in the developed world, typically is a chronic… (More)
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Highly Cited
2003
Highly Cited
2003
Palpable swelling of regional lymph nodes is a common sequela of microbial infections but the mechanism responsible for the… (More)
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Highly Cited
2000
Highly Cited
2000
The linker molecule LAT is a substrate of the tyrosine kinases activated following TCR engagement of T cells. LAT is also… (More)
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Highly Cited
1997
Highly Cited
1997
Mast cells are the main effector cells of immediate hypersensitivity and anaphylaxis. Their role in the development of allergen… (More)
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Highly Cited
1996
Highly Cited
1996
Mast cells play a key role in inflammatory reactions triggered by tissue injury or immune perturbations. Little is known about… (More)
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Highly Cited
1995
Highly Cited
1995
Mast cells are multifunctional bone marrow-derived cells found in mucosal and connective tissues and in the nervous system, where… (More)
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Highly Cited
1994
Highly Cited
1994
Mast cells and nerve growth factor (NGF) have both been reported to be involved in neuroimmune interactions and tissue… (More)
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Highly Cited
1982
Highly Cited
1982
Anti-IgE-dependent activation of rat and human mast cells resulted in the preferential generation of the cyclooxygenase products… (More)
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