manumycin

Known as: 2,4-Decadienamide, N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-2,4,6-trimethyl-, UCFI-C, manumycin A 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2017
05101519632017

Papers overview

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2013
2013
Therapy resistance can be attributed to acquisition of anti-apoptotic mechanisms by the cancer cells. Therefore, developing… (More)
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2007
2007
OBJECTIVE Statins are presumed to exert their antiatherogenic effects in part via lipid-lowering-independent mechanisms… (More)
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2006
2006
IkappaB kinase (IKK) catalytic subunits play a key role in cytokinemediated nuclear factor (NF)-kappaB signaling, and a loss of… (More)
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2002
2002
Interleukin 6 (IL-6) is an important survival and growth factor for myeloma cells and exerts its effects by activating several… (More)
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2001
2001
Our laboratory has investigated the anticancer effects of combined manumycin (a farnesyltransferase inhibitor) and paclitaxel (a… (More)
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2001
2001
We previously demonstrated that the combination of a farnesyltransferase inhibitor, manumycin A, and paclitaxel had a synergistic… (More)
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2000
2000
Despite the current multimodal approach to treatment of anaplastic thyroid cancer (ATC), the prognosis for patients with the… (More)
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1999
1999
Restenosis after angioplasty is thought to be caused by proliferation and migration of vascular smooth muscle cells (VSMCs), and… (More)
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Highly Cited
1998
Highly Cited
1998
Recent evidence suggests that apoptosis may be involved in the control of vascular smooth muscle cell (VSMC) number in… (More)
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1997
1997
The effects of manumycin, a competitive farnesyltransferase (FTase) inhibitor, on pancreatic cancer cell lines with or without K… (More)
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