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manumycin

Known as: 2,4-Decadienamide, N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-2,4,6-trimethyl-, UCFI-C, manumycin a 
 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Emerging evidence links exosomes to cancer progression by the trafficking of oncogenic factors and neoplastic reprogramming of… Expand
Highly Cited
2013
Highly Cited
2013
Therapy resistance can be attributed to acquisition of anti-apoptotic mechanisms by the cancer cells. Therefore, developing… Expand
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2007
2007
Background:  The formation of methylglyoxal (MGO), a highly reactive dicarbonyl compound, is accelerated under diabetic… Expand
Highly Cited
2002
Highly Cited
2002
We have recently shown that green tea polyphenols, and especially (-)-epigallocatechin 3-gallate (EGCg), acted as potent… Expand
Highly Cited
2001
Highly Cited
2001
Our laboratory has investigated the anticancer effects of combined manumycin (a farnesyltransferase inhibitor) and paclitaxel (a… Expand
Highly Cited
2001
Highly Cited
2001
This report describes 2 patients with a clinical and hematologic diagnosis of chronic myeloid leukemia (CML) in chronic phase who… Expand
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Highly Cited
2000
Highly Cited
2000
Despite the current multimodal approach to treatment of anaplastic thyroid cancer (ATC), the prognosis for patients with the… Expand
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Highly Cited
1996
Highly Cited
1996
Activating mutations of Ki‐ras have been detected in most human pancreatic adenocarcinomas. Since Ras protein requires… Expand
Highly Cited
1993
Highly Cited
1993
A microbial screen using a yeast strain with conditional deficiency in the GPA1 gene was carried out to search for inhibitors of… Expand
1987
1987
Manumycin (1), produced by Streptomyces parvulus (strain Tu 64), was isolated from the mycelium by extraction with acetone and… Expand
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