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mannose binding

Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in… Expand
National Institutes of Health

Papers overview

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2016
2016
The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target?
FimH is a bacterial lectin found at the tips of type 1 pili of uropathogenic Escherichia coli (UPEC). It mediates shear‐enhanced… Expand
2015
2015
Modeling Protein Ligand Interactions Using Multi-Scale Computational Approaches
 
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2014
2014
Dynamic modulation of fimbrial extension and FimH-mannose binding force on live bacteria under pH changes: a molecular atomic force microscopy analysis.
Mechanical and conformational properties of type 1 fimbriae were evaluated on live bacterial cells by Single Molecule Force… Expand
Highly Cited
2009
Highly Cited
2009
Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding
FimH, the type 1 pilus adhesin of uropathogenic Escherichia coli (UPEC), contains a receptor-binding domain with an acidic… Expand
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Highly Cited
2007
Highly Cited
2007
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants.
Carbohydrate-protein interactions on surface and in solution were quantitatively measured by a glycan microarray. Assessing… Expand
2007
2007
A novel tetrameric lectin from Lycoris aurea with four mannose binding sites per monomer.
The mannose-binding agglutinin from bulbs of Lycoris aurea (LAA) agglutinates rabbit but not human erythrocytes. The molecular… Expand
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Highly Cited
2001
Highly Cited
2001
The mannose binding lectin gene influences the severity of chronic liver disease in cystic fibrosis
Chronic liver disease is a major complication of cystic fibrosis. Its incidence and severity show marked heterogeneity, even… Expand
2000
2000
Sequence and structural determinants of mannose recognition
Mannose, an abundant cell surface monosaccharide binds to a diverse set of receptors, which are involved in a variety of… Expand
Highly Cited
1999
Highly Cited
1999
Intestinal IgA: novel views on its function in the defence of the largest mucosal surface
The intestine is undoubtedly the most misunderstood and under-appreciated lymphoid organ in the body. Yet, in the eyes of mucosal… Expand
Highly Cited
1999
Highly Cited
1999
Crystal structure of a dimeric mannose-specific agglutinin from garlic: quaternary association and carbohydrate specificity.
A mannose-specific agglutinin, isolated from garlic bulbs, has been crystallized in the presence of a large excess of alpha-d… Expand
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