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mannose binding

Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in… Expand
National Institutes of Health

Papers overview

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2016
2016
The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target?
FimH is a bacterial lectin found at the tips of type 1 pili of uropathogenic Escherichia coli (UPEC). It mediates shear-enhanced… Expand
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2014
2014
Dynamic modulation of fimbrial extension and FimH-mannose binding force on live bacteria under pH changes: a molecular atomic force microscopy analysis.
Mechanical and conformational properties of type 1 fimbriae were evaluated on live bacterial cells by Single Molecule Force… Expand
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2013
2013
Mannose Binding Lectin Deficiency and Clinical Features
Innate immunity consists of macrophages, neutrophils, natural killer cells, mucosal immunuglobulins and the comlement system… Expand
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Highly Cited
2009
Highly Cited
2009
Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding
FimH, the type 1 pilus adhesin of uropathogenic Escherichia coli (UPEC), contains a receptor-binding domain with an acidic… Expand
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Highly Cited
2007
Highly Cited
2007
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants.
Carbohydrate-protein interactions on surface and in solution were quantitatively measured by a glycan microarray. Assessing… Expand
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2007
2007
A novel tetrameric lectin from Lycoris aurea with four mannose binding sites per monomer.
The mannose-binding agglutinin from bulbs of Lycoris aurea (LAA) agglutinates rabbit but not human erythrocytes. The molecular… Expand
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2001
2001
The mannose binding lectin gene influences the severity of chronic liver disease in cystic fibrosis.
Chronic liver disease is a major complication of cystic fibrosis. Its incidence and severity show marked heterogeneity, even… Expand
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2000
2000
Sequence and structural determinants of mannose recognition.
Mannose, an abundant cell surface monosaccharide binds to a diverse set of receptors, which are involved in a variety of… Expand
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1999
1999
Crystal structure of a dimeric mannose-specific agglutinin from garlic: quaternary association and carbohydrate specificity.
A mannose-specific agglutinin, isolated from garlic bulbs, has been crystallized in the presence of a large excess of alpha-d… Expand
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Highly Cited
1999
Highly Cited
1999
Intestinal IgA: novel views on its function in the defence of the largest mucosal surface.
The intestine is undoubtedly the most misunderstood and under-appreciated lymphoid organ in the body. Yet, in the eyes of mucosal… Expand
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