mRNA Surveillance

mRNA Surveillance works within elaborate cellular mechanisms to ensure accurate gene expression by assessing suitable mRNA quality for translation… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Several recent studies in a number of model systems including zebrafish, Arabidopsis, and mouse have revealed phenotypic… (More)
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Review
2005
Review
2005
Nonsense-mediated mRNA decay (NMD) is an mRNA surveillance pathway that ensures the rapid degradation of mRNAs containing… (More)
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Highly Cited
2004
Highly Cited
2004
Nuclear export of mRNA is a central step in gene expression that shows extensive coupling to transcription and transcript… (More)
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Highly Cited
2004
Highly Cited
2004
Nonsense mutations influence several aspects of gene expression, including mRNA stability and splicing fidelity, but the… (More)
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Highly Cited
2004
Highly Cited
2004
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that eliminates mRNAs containing premature termination codons… (More)
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Highly Cited
2003
Highly Cited
2003
Eukaryotic mRNAs containing premature termination codons (PTCs) are degraded by a process known as nonsense-mediated mRNA decay… (More)
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Review
2002
Review
2002
In eukaryotes, an elaborate set of mechanisms has evolved to ensure that the multistep process of gene expression is accurately… (More)
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Highly Cited
2002
Highly Cited
2002
Translation is an important mechanism to monitor the quality of messenger RNAs (mRNAs), as exemplified by the translation… (More)
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Review
1999
Review
1999
A conserved mRNA degradation system, referred to as mRNA surveillance, exists in eukaryotic cells to degrade aberrant mRNAs. A… (More)
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Highly Cited
1999
Highly Cited
1999
The mRNA surveillance system is known to rapidly degrade aberrant mRNAs that contain premature termination codons in a process… (More)
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