m1-toxin

We report the characterization, by combination of high-resolution on-line molecular mass and disulfide bond profiling and top… (More)

Rat sublingual gland M2 and M3 muscarinic receptors each directly activate exocrine secretion. To investigate the functional role… (More)

The venom of the green mamba, Dendroaspis angusticeps, was found to have at least six trace m1-specific toxins that block the… (More)

Activation of muscarinic acetylcholine (ACh) receptors (mAChRs) increases excitability of pyramidal cells by inhibiting several K… (More)

Evidence suggests that cholinergic input to the hippocampus plays an important role in learning and memory and that degeneration… (More)

We investigated the role of M1 and M3 receptors in regulating exocrine secretion from acini isolated from rat sublingual glands… (More)

Toxins from the venom of the African green mamba, Dendroaspis angusticeps, fulfill a major need for selective ligands for some of… (More)

m1-Toxin was found to slow the dissociation of [3H]N-methyl-scopolamine (NMS) and [3H]pirenzepine from m1 muscarinic receptors… (More)

The venom of the Eastern green mamba from Africa, Dendroaspis angusticeps, was found to block the binding of 3H-quinuclidinyl… (More)

m1-Toxin is the only ligand which is known to bind specifically to the extracellular face of genetically defined m1 muscarinic… (More)