m1-toxin

Rat sublingual gland M2 and M3 muscarinic receptors each directly activate exocrine secretion. To investigate the functional role… Expand

Activation of muscarinic acetylcholine (ACh) receptors (mAChRs) increases excitability of pyramidal cells by inhibiting several K… Expand

The venom of the green mamba, Dendroaspis angusticeps, was found to have at least six trace m1-specific toxins that block the… Expand

Evidence suggests that cholinergic input to the hippocampus plays an important role in learning and memory and that degeneration… Expand

Toxins from the venom of the African green mamba, Dendroaspis angusticeps, fulfill a major need for selective ligands for some of… Expand

We investigated the role of M1 and M3 receptors in regulating exocrine secretion from acini isolated from rat sublingual glands… Expand

The venom of the Eastern green mamba from Africa, Dendroaspis angusticeps, was found to block the binding of 3H-quinuclidinyl… Expand

m1-Toxin was found to slow the dissociation of [3H]N-methyl-scopolamine (NMS) and [3H]pirenzepine from m1 muscarinic receptors… Expand

m1-Toxin is the only ligand which is known to bind specifically to the extracellular face of genetically defined m1 muscarinic… Expand

The tiny island of South Bimini contains 4 species of lizards of the genus Anolis, a number surpassed only on the 4 largest… Expand