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lysyl-isoleucyl-phenylalanyl-methionyl-lysine

Known as: KIFMK, Lys-Ile-Phe-Met-Lys 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2014
01219962014

Related topics

Related topics

2 relations

Broader (2)

OligopeptidesSodium Channel Blockers

Related mentions per year

Related mentions per year

1954-2018
1960198020002020
lysyl-isoleucyl-phenylalanyl-methionyl-lysine
Oligopeptides
Sodium Channel Blockers

Papers overview

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2014
2014
Experimental design-guided development of a stereospecific capillary electrophoresis assay for methionine sulfoxide reductase enzymes using a diastereomeric pentapeptide substrate.
A capillary electrophoresis method has been developed and validated to evaluate the stereospecific activity of recombinant human… (More)
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2004
2004
Suppression of insulin signalling by a synthetic peptide KIFMK suggests the cytoplasmic linker between DIII-S6 and DIV-S1 as a local anaesthetic binding site on the sodium channel.
1. Acetyl-KIFMK-amide (KIFMK) restores fast inactivation to mutant sodium channels having a defective inactivation gate. Its… (More)
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2003
2003
Oligopeptide-mediated helix stabilization of model peptides in aqueous solution.
Oligopeptide-mediated helix stabilization of peptides in hydrophobic solutions was previously found by NMR and CD spectroscopic… (More)
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2003
2003
Role of an $4-$5 Linker in Sodium Channel Inactivation Probed by Mutagenesis and a Peptide Blocker
A pair of conserved methionine residues, located on the cytoplasmic linker between segments $4 and $5 in the fourth domain of… (More)
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2001
2001
Helix-stabilizing effects of the pentapeptide KIFMK and its related peptides on the sodium channel inactivation gate peptides.
We have previously found by NMR and CD spectroscopic studies that the helical content of the sodium channel inactivation gate… (More)
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1999
1999
A human muscle Na+ channel mutation in the voltage sensor IV/S4 affects channel block by the pentapeptide KIFMK.
1. Whole cell patch clamping of transfected HEK293 cells was used to examine the effects of a pentapeptide (KIFMK) containing the… (More)
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1999
1999
1H-NMR and circular dichroism spectroscopic studies on changes in secondary structures of the sodium channel inactivation gate peptides as caused by the pentapeptide KIFMK.
The pentapeptide KIFMK, which contains three clustered hydrophobic amino acid residues of isoleucine, phenylalanine, and… (More)
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1998
1998
Kinetic Analysis of Block of Open Sodium Channels by a Peptide Containing the Isoleucine, Phenylalanine, and Methionine (IFM) Motif from the Inactivation Gate
We analyzed the kinetics of interaction between the peptide KIFMK, containing the isoleucine, phen-ylalanine, and methionine (IFM… (More)
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1997
1997
Competition for Binding Between Veratridine and KIFMK: An Open Channel Blocking Peptide of the RIIA Sodium Channel
Veratridine, an alkaloid isolated from the rhizome of V. album, binds and slows the inactivation of the brain sodium channels… (More)
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1996
1996
Role of an S4-S5 linker in sodium channel inactivation probed by mutagenesis and a peptide blocker
A pair of conserved methionine residues, located on the cytoplasmic linker between segments S4 and S5 in the fourth domain of… (More)
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