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lysyl-isoleucyl-phenylalanyl-methionyl-lysine
Known as:
KIFMK
, Lys-Ile-Phe-Met-Lys
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Oligopeptides
Sodium Channel Blockers
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Experimental design-guided development of a stereospecific capillary electrophoresis assay for methionine sulfoxide reductase enzymes using a diastereomeric pentapeptide substrate.
Q. Zhu
,
Xingyu Huo
,
S. Heinemann
,
R. Schoenherr
,
Rabab G. El-Mergawy
,
G. Scriba
Journal of chromatography. A
2014
Corpus ID: 21884371
A capillary electrophoresis method has been developed and validated to evaluate the stereospecific activity of recombinant human…
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2008
2008
Ryanoids and imperatoxin affect the modulation of cardiac ryanodine receptors by dihydropyridine receptor Peptide A.
M. Porta
,
P. Diaz-Sylvester
,
A. Nani
,
J. Ramos-Franco
,
J. Copello
Biochimica et biophysica acta
2008
Corpus ID: 28372944
Ca(2+)-entry via L-type Ca(2+) channels (DHPR) is known to trigger ryanodine receptor (RyR)-mediated Ca(2+)-release from…
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2004
2004
Suppression of insulin signalling by a synthetic peptide KIFMK suggests the cytoplasmic linker between DIII‐S6 and DIV‐S1 as a local anaesthetic binding site on the sodium channel
M. Hirose
,
Y. Kuroda
,
+4 authors
Y. Tanaka
British journal of pharmacology
2004
Corpus ID: 11857073
Acetyl‐KIFMK‐amide (KIFMK) restores fast inactivation to mutant sodium channels having a defective inactivation gate. Its binding…
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1999
1999
Block of Brain Sodium Channels by Peptide Mimetics of the Isoleucine, Phenylalanine, and Methionine (IFM) Motif from the Inactivation Gate
Galen Eaholtz
,
A. Colvin
,
D. Leonard
,
C. Taylor
,
W. Catterall
The Journal of general physiology
1999
Corpus ID: 1210777
Inactivation of sodium channels is thought to be mediated by an inactivation gate formed by the intracellular loop connecting…
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1999
1999
1H-NMR and circular dichroism spectroscopic studies on changes in secondary structures of the sodium channel inactivation gate peptides as caused by the pentapeptide KIFMK.
Y. Kuroda
,
Y. Maeda
,
+5 authors
T. Nakagawa
Biophysical journal
1999
Corpus ID: 12616605
The pentapeptide KIFMK, which contains three clustered hydrophobic amino acid residues of isoleucine, phenylalanine, and…
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1999
1999
A human muscle Na+ channel mutation in the voltage sensor IV/S4 affects channel block by the pentapeptide KIFMK
W. Peter
,
N. Mitrović
,
M. Schiebe
,
F. Lehmann-Horn
,
H. Lerche
The Journal of physiology
1999
Corpus ID: 1899281
1 Whole cell patch clamping of transfected HEK293 cells was used to examine the effects of a pentapeptide (KIFMK) containing the…
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Highly Cited
1998
Highly Cited
1998
A Critical Role for the S4-S5 Intracellular Loop in Domain IV of the Sodium Channel α-Subunit in Fast Inactivation*
J. C. McPhee
,
D. S. Ragsdale
,
T. Scheuer
,
W. Catterall
The Journal of Biological Chemistry
1998
Corpus ID: 19185105
Na+ channel fast inactivation is thought to involve the closure of an intracellular inactivation gate over the channel pore…
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1998
1998
Kinetic Analysis of Block of Open Sodium Channels by a Peptide Containing the Isoleucine, Phenylalanine, and Methionine (IFM) Motif from the Inactivation Gate
Galen Eaholtz
,
W. Zagotta
,
W. Catterall
The Journal of general physiology
1998
Corpus ID: 1971245
We analyzed the kinetics of interaction between the peptide KIFMK, containing the isoleucine, phen-ylalanine, and methionine (IFM…
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1997
1997
Competition for Binding Between Veratridine and KIFMK: An Open Channel Blocking Peptide of the RIIA Sodium Channel
A. S. Ghatpande
,
S. Sikdar
The Journal of Membrane Biology
1997
Corpus ID: 21388432
Abstract. Veratridine, an alkaloid isolated from the rhizome of V. album, binds and slows the inactivation of the brain sodium…
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Highly Cited
1996
Highly Cited
1996
Role of an S4-S5 linker in sodium channel inactivation probed by mutagenesis and a peptide blocker
Lei Jun Tang
,
R. Kallen
,
R. Horn
The Journal of general physiology
1996
Corpus ID: 9096954
A pair of conserved methionine residues, located on the cytoplasmic linker between segments S4 and S5 in the fourth domain of…
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