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lysosomal transport

The directed movement of substances into, out of or within a lysosome. [GOC:ai]
National Institutes of Health

Papers overview

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2016
2016
The lysosomal integral membrane protein type-2 (LIMP-2) plays a pivotal role in the delivery of β-glucocerebrosidase (GC) to… Expand
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2013
2013
Cystinosis is a lysosomal storage disorder caused by the accumulation of the amino acid cystine due to genetic defects in the… Expand
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2012
2012
The transport of lysosomal proteins is, in general, mediated by mannose 6-phosphate receptors via carbohydrate modifications… Expand
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2012
2012
UNLABELLED Enzyme replacement therapies for lysosomal storage disorders are often hindered by suboptimal biodistribution of… Expand
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2009
2009
Nonalcoholic fatty liver disease (NAFLD) affects up to 30% of adults in the United States and is associated with obesity… Expand
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2009
2009
BackgroundNeuronal ceroid lipofuscinoses (NCLs) comprise at least eight genetically characterized neurodegenerative disorders of… Expand
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2008
2008
The AP-3 adaptor complex targets selected transmembrane proteins to lysosomes and lysosome-related organelles. We reconstituted… Expand
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Highly Cited
2007
Highly Cited
2007
Defects in lysosomal trafficking pathways lead to decreased cell viability and are associated with progressive disorders in… Expand
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Highly Cited
2001
Highly Cited
2001
Many intracellular compartments, including MHC class II-containing lysosomes, melanosomes, and phagosomes, move along… Expand
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Highly Cited
1990
Highly Cited
1990
Lysosomes constitute only 4% of the intracellular volume of a normal human fibroblast. When human fibroblasts are incubated for 2… Expand
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