lysosomal proteolysis

Exercise improves cognitive function in older adults, but the underlying mechanism is largely unknown. Both lysosomal degradation… (More)

Autophagy is a dynamic recycling system using lysosomal proteolysis that produces new proteins and energy for cellular renovation… (More)

Necrosis, one of the two main types of cell death, contributes critically in many devastating pathological conditions in human… (More)

Mutations in genes for presenilins (PS1 and PS2) lead to early-onset familial Alzheimer’s disease (FAD). It was recently shown… (More)

Antigen-presenting cells (APCs) internalize antigens and present antigen-derived peptides to T cells. Although APCs have been… (More)