lutetium Lu 177 monoclonal antibody CC49
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Current pretargeting systems use noncovalent biologic interactions, which are prone to immunogenicity. We previously developed a… Expand While (188)Re has been used successfully in mice for tumor radiotherapy by MORF/cMORF pretargeting, previous radiolabeling of the… Expand Carcinoembryonic antigen (CEA) is a sensitive marker for detecting recurrent colorectal carcinoma. An asymptomatic rise of CEA… Expand BACKGROUND
Carcinoembryonic antigen (CEA) is a sensitive marker for detecting recurrent colorectal carcinoma. An asymptomatic… Expand Progress in the use of monoclonal antibodies (MAbs) for the treatment of solid tumors is limited by a number of factors… Expand Monoclonal antibody (mAb) CC49, a murine IgG1, reacts with the tumor-associated glycoprotein-72 expressed on a variety of… Expand Our previous results indicated that the trihydroxamate ligand, trisuccin, was a promising bifunctional chelating agent (BCA) for… Expand CC49 is a second-generation monoclonal antibody (MAb) that has high affinity for the tumor-associated pancarcinoma antigen tumor… Expand Background. Radiolabeled CC49, a second generation high affinity monoclonal antibody (MoAb) reactive with tumor‐associated… Expand The moderately differentiated human colon tumor cell line, HT-29, constitutively expresses low levels of the high molecular… Expand