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lutetium Lu 177 monoclonal antibody CC49

Known as: 177 Lu-CC49, Lu177 MOAB CC49 
A radioimmunoconjugate of the humanized monoclonal antibody (MoAb) CC49 labeled with lutetium 131 (Lu-177). MoAb CC49 binds to the pancarcinoma tumor… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Current pretargeting systems use noncovalent biologic interactions, which are prone to immunogenicity. We previously developed a… Expand
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2011
2011
While (188)Re has been used successfully in mice for tumor radiotherapy by MORF/cMORF pretargeting, previous radiolabeling of the… Expand
2000
2000
Carcinoembryonic antigen (CEA) is a sensitive marker for detecting recurrent colorectal carcinoma. An asymptomatic rise of CEA… Expand
Review
2000
Review
2000
BACKGROUND Carcinoembryonic antigen (CEA) is a sensitive marker for detecting recurrent colorectal carcinoma. An asymptomatic… Expand
1999
1999
Progress in the use of monoclonal antibodies (MAbs) for the treatment of solid tumors is limited by a number of factors… Expand
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1999
1999
Monoclonal antibody (mAb) CC49, a murine IgG1, reacts with the tumor-associated glycoprotein-72 expressed on a variety of… Expand
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1997
1997
Our previous results indicated that the trihydroxamate ligand, trisuccin, was a promising bifunctional chelating agent (BCA) for… Expand
Highly Cited
1995
Highly Cited
1995
CC49 is a second-generation monoclonal antibody (MAb) that has high affinity for the tumor-associated pancarcinoma antigen tumor… Expand
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Highly Cited
1994
Highly Cited
1994
Background. Radiolabeled CC49, a second generation high affinity monoclonal antibody (MoAb) reactive with tumor‐associated… Expand
Highly Cited
1993
Highly Cited
1993
The moderately differentiated human colon tumor cell line, HT-29, constitutively expresses low levels of the high molecular… Expand
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