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lonazolac

Known as: 3-(4-chlorophenyl)-1-phenylpyrazole-4-acetic acid 
 
National Institutes of Health

Papers overview

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2018
2018
Twelve new compounds of 1,3,4-trisubstituted-pyrazole derivatives possessing two cyclooxygenase-2 (COX-2) pharmacophoric moieties… Expand
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2012
2012
mPGES-1 is a promising target for development of new anti-inflammatory drugs. We aimed to create mPGES-1 inhibitors by modifying… Expand
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2009
2009
A novel series of 1,3-diarylpyrazole derivatives (4–8), analogues to lonazolac, were designed, synthesized, and evaluated for… Expand
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2002
2002
A reliable method, which can be used for the determination of lonazolac and its hydroxylated and O-sulfated metabolites in cell… Expand
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2001
2001
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used as analgesic and anti-rheumatic drugs, and they are often misused… Expand
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1991
1991
The gastric acid antisecretory compound omeprazole (5-methoxy-2-((4-methoxy- 3,5-dimethyl-2-pyridinylmethyl)-sulphinyl)-1H… Expand
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1990
1990
The effects of Lonazolac calcium in modulating histamine release, leukotriene and 12-HETE generation and PAF metabolism from… Expand
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1986
1986
Single doses of indoprofen 100 mg and lonazolac-Ca 200 mg were given orally to eight healthy volunteers. Blood samples were taken… Expand
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1985
1985
The immunological effect of lonazolac on mononuclear cell activation has been investigated using the indirect Leukocyte Adherence… Expand
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1981
1981
Calcium-[3-(p-chlorophenyl)-1-phenylpyrazole-4]-acetate (Lonazolac-Ca, active principle of Irritren) is a new antiinflammatory… Expand
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