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lodoxamide tromethamine

Known as: 2,2'-((2-chloro-5-cyano-1,3-phenylene)diimino)bis(2-oxoacetic acid), compd. with 2-amino-2- (hydroxymethyl)-1,3-propanediol (1:2), lodoxamide tromethamine [Chemical/Ingredient] 
The tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity. Upon administration to the eye… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
To determine the role of mast cells in ischaemia–reperfusion (IR) injury to skeletal muscle, Wf/Wf mast cell‐deficient and their… Expand
Highly Cited
1997
Highly Cited
1997
AIM To validate the use of tear eosinophil cationic protein (ECP) as a marker for eosinophil activation, and its pharmacological… Expand
1997
1997
PURPOSE The purpose of the study is to evaluate in a double-blind, randomized study the efficacy of lodoxamide tromethamine 0.1… Expand
1995
1995
PURPOSE We studied the efficacy of topically applied lodoxamide tromethamine 0.1% in the treatment of superior limbic… Expand
1994
1994
Lodoxamide is an antiallergic compound. The present study evaluated the efficacy on clinical and cytological parameters and… Expand
Highly Cited
1989
Highly Cited
1989
These studies were designed to assess pathophysiologic factors responsible for increased vascular permeability occurring in rat… Expand
Highly Cited
1988
Highly Cited
1988
Leukocyte-mediated myocardial reperfusion injury is characterized by the progressive migration and accumulation of… Expand
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1985
1985
The efficacy of lodoxamide tromethamine in the treatment of asthma was studied in a 16-week double-blind, placebo-controlled… Expand
1982
1982
The beneficial effects of lodoxamide tromethamine (U42585E) have been examined in a canine model of myocardial ischemic injury… Expand
1980
1980
Lodoxamide tromethamine (U-42,585E) is a new drug intended for prophylaxis of mast cell-mediated allergic disease. It is a water… Expand