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lodamin

Known as: mPEG-PLA-TNP-470 
 
National Institutes of Health

Papers overview

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2013
2013
Chronic and recurrent uveitis account for approximately 10% of legal blindness in the western world. Autoimmune uveitis is driven… Expand
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2013
2013
Lodamin, the oral formulation of TNP-470, a methionine aminopeptidase 2 (MetAp2) inhibitor, was previously shown to significantly… Expand
Highly Cited
2011
Highly Cited
2011
Endometriosis is a debilitating disease characterized by the growth of ectopic endometrial tissue. It is widely accepted that… Expand
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2010
2010
Pathological neovascularization is a hallmark of late stage neovascular (wet) age-related macular degeneration (AMD) and the… Expand
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2010
2010
Abstract : Centers on the development of new medical therapies and regenerative medicine approaches for the treatment of injured… Expand
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Highly Cited
2008
Highly Cited
2008
Targeting angiogenesis, the formation of blood vessels, is an important modality for cancer therapy. TNP-470, a fumagillin analog… Expand
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2008
2008
Despite promising early results, cancer therapy aimed at selective destruction of tumor blood vessels faces several hurdles… Expand
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2008
2008
1118 Targeting angiogenesis, the formation of new blood vessels, is becoming an important strategy for cancer therapy. TNP-470… Expand
2008
2008
769 possibly breast cancers4,5. However, in most advanced tumors, the response to antiangiogenic therapy, even in combination… Expand
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2008
2008
  • P. Goymer
  • Nature Reviews Cancer
  • 2008
  • Corpus ID: 46098883
inhibitor TNP-470 is a potent suppressor of tumour growth and metastasis, but its use is limited because it requires lengthy… Expand