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lipoyllysine

 
National Institutes of Health

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3 relations

Broader (2)

LysineThioctic Acid
analogs & derivatives

Papers overview

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2009
2009
A unique lipoylation system in the Archaea. Lipoylation in Thermoplasma acidophilum requires two proteins.
Members of the 2-oxoacid dehydrogenase multienzyme complex family play a key role in the pathways of central metabolism. Post… Expand
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2008
2008
Selective and sensitive determination of lipoyllysine (protein-bound alpha-lipoic acid) in biological specimens by high-performance liquid chromatography with fluorescence detection.
The direct determination of lipoyllysine (LLys) in proteins was carried out by reversed-phase high-performance liquid… Expand
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2006
2006
T cell targeting and phagocytosis of apoptotic biliary epithelial cells in primary biliary cirrhosis.
Primary biliary cirrhosis (PBC) is characterized by loss of tolerance against ubiquitously expressed mitochondrial autoantigens… Expand
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1998
1998
Skeletal muscle and liver lipoyllysine content in response to exercise, training and dietary alpha-lipoic acid supplementation.
In human cells, alpha-lipoic acid (LA) is present in a bound lipoyllysine form in mitochondrial proteins that play a central role… Expand
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1998
1998
Assay of protein-bound lipoic acid in tissues by a new enzymatic method.
A new enzymatic method for the determination of protein-bound lipoic acid was established. Bound lipoyl groups were liberated in… Expand
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1998
1998
Redox regulation of cell functions by α‐lipoate: biochemical and molecular aspects
α-lipoate also known as thioctic acid, 1,2-dithiolane-3-pentanoic acid, 1,2-dithiolane-3-valeric acid or 6,8-thioctic acid has… Expand
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1997
1997
Receptor site and stereospecifity of dihydrolipoamide dehydrogenase for R- and S-lipoamide: a molecular modeling study.
The binding of the substrate R-dihydrolipoamide to the active site of dihydrolipoamide dehydrogenase has been investigated by… Expand
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1991
1991
Lipoylation of H-protein of the glycine cleavage system. The effect of site-directed mutagenesis of amino acid residues around the lipoyllysine residue on the lipoate attachment.
H-protein of the glycine cleavage system has lipoic acid on the Lys59 residue. Comparison of amino acid sequences around the… Expand
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1989
1989
Determination of lipoyllysine derived from enzymes by liquid chromatography.
Lipoyllysine was liberated from the commercial enzymes bovine heart alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase… Expand
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1989
1989
Kinetics and specificity of reductive acylation of lipoyl domains from 2-oxo acid dehydrogenase multienzyme complexes.
Lipoamide and a peptide, Thr-Val-Glu-Gly-Asp-Lys-Ala-Ser-Met-Glu lipoylated on the N6-amino group of the lysine residue, were… Expand
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