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liposomal vinorelbine

A formulation of the semisynthetic vinca alkaloid, vinorelbine, encapsulated within liposomes, with antineoplastic activity. Vinorelbine binds to… Expand
National Institutes of Health

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2017
2017
Lung cancer is the leading cause of cancer-related death worldwide. Most targeted drugs approved for lung cancer treatment are… Expand
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2015
2015
Colorectal cancer is one of the most commonly diagnosed cancers and a leading cause of cancer mortality worldwide. Current… Expand
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2012
2012
Liposomal vinorelbine formulation is desirable, as it might improve the therapeutic activity of vinorelbine. However, because of… Expand
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2012
2012
BACKGROUND The combination of a radioisotope with a chemotherapeutic agent in a liposomal carrier (ie, Indium-111-labeled… Expand
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2011
2011
OBJECTIVES Pegylated liposome formulations of vinorelbine with prolonged circulation half-life (t½) are desirable. However, DSPE… Expand
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2010
2010
Prolonged vinorelbine exposure is correlated with improved antineoplastic effects, as evidenced by increased response rate in… Expand
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2010
2010
SummaryPurpose This phase I study was performed to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of… Expand
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2009
2009
UNLABELLED In our previous studies using combined radioisotopes with chemotherapeutic liposomal drugs (i.e., (111)In-labeled… Expand
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2009
2009
Effective liposomal formulations of vinorelbine (5' nor-anhydro-vinblastine; VRL) have been elusive due to vinorelbine's… Expand
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Highly Cited
2008
Highly Cited
2008
The cancer stem cells play a critical role in both initiation and relapse of the cancers as they are resistant to the most of… Expand
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