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Most physiology and behavior of mammalian organisms follow daily oscillations. These rhythmic processes are governed by… Expand Although homogeneous gold catalysis was known previously, an exponential growth was only induced 12 years ago. The key findings… Expand Highly potent, but poorly water-soluble, drug candidates are common outcomes of contemporary drug discovery programmes and… Expand Cholesterol-conjugated siRNAs can silence gene expression in vivo. Here we synthesize a variety of lipophilic siRNAs and use them… Expand Mitochondrial oxidative damage contributes to a range of degenerative diseases. Consequently, the selective inhibition of… Expand Both lipophilic and hydrophilic antioxidant capacities were determined using the oxygen radical absorbance capacity (ORAC(FL… Expand The oral delivery of hydrophobic drugs presents a major challenge because of the low aqueous solubility of such compounds. Self… Expand A method for the screening of antioxidant activity is reported as a decolorization assay applicable to both lipophilic and… Expand The recent explosion of interest in the bioactivity of the flavonoids of higher plants is due, at least in part, to the potential… Expand By using a potential-dependent J-aggregate-forming delocalized lipophilic cation, 5,5',6,6'-tetrachloro-1,1',3,3… Expand