lipophilicity

Known as: lipophilic 
Lipophilicity represents the affinity of a molecule or a moiety for a lipophilic environment. It is commonly measured by its distribution behavior in… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Urea-based inhibitors of the prostate-specific membrane antigen (PSMA) represent low-molecular-weight pepidomimetics showing the… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Cross-sectional reports suggest that statin users are less likely to have Alzheimer disease (AD). Prospective studies… (More)
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Highly Cited
2007
Highly Cited
2007
Cholesterol-conjugated siRNAs can silence gene expression in vivo. Here we synthesize a variety of lipophilic siRNAs and use them… (More)
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Highly Cited
2006
Highly Cited
2006
A novel scoring function to estimate protein-ligand binding affinities has been developed and implemented as the Glide 4.0 XP… (More)
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Highly Cited
2003
Highly Cited
2003
Methods are described for the extraction and analysis of hydrophilic and lipophilic antioxidants, using modifications of the… (More)
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Review
2000
Review
2000
There are currently about 10000 drug-like compounds. These are sparsely, rather than uniformly, distributed through chemistry… (More)
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Highly Cited
2000
Highly Cited
2000
The cause of Parkinson's disease (PD) is unknown, but epidemiological studies suggest an association with pesticides and other… (More)
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Highly Cited
1999
Highly Cited
1999
A method for the screening of antioxidant activity is reported as a decolorization assay applicable to both lipophilic and… (More)
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Highly Cited
1993
Highly Cited
1993
A new method for the cytofluorimetric analysis of mitochondrial membrane potential in intact cells has been developed by using… (More)
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Highly Cited
1991
Highly Cited
1991
By using a potential-dependent J-aggregate-forming delocalized lipophilic cation, 5,5',6,6'-tetrachloro-1,1',3,3… (More)
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