linoleoyl-CoA desaturase

Known as: Delta 6 Fatty Acid Desaturase, Delta 6 Desaturase, Fatty Acid Delta 6 Desaturase 
An enzyme that catalyzes the syn-dehydrogenation of linoleol-CoA gamma-linolenoyl-CoA. It was formerly characterized as EC 1.14.99.25.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND The long-term role of fatty acids (FAs) in the cause of diabetes remains largely unclear. OBJECTIVE We aimed to… (More)
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2009
2009
BACKGROUND Conversion of linoleic acid (LA) and alpha-linolenic acid (ALA) to their higher chain homologues in humans depends on… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Desaturase indexes, as markers of endogenous fatty acid desaturation, and a characteristic serum fatty acid (FA… (More)
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Highly Cited
2006
Highly Cited
2006
Fatty acid elongases and desaturases play an important role in hepatic and whole body lipid composition. We examined the role… (More)
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Review
2004
Review
2004
Fatty acid desaturases introduce a double bond in a specific position of long-chain fatty acids, and are conserved across… (More)
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Highly Cited
2003
Highly Cited
2003
Mitochondrial cardiolipin (CL) contains unique fatty acid patterns, but it is not known how the characteristic molecular species… (More)
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Highly Cited
2002
Highly Cited
2002
In the process of seeking sterol regulatory element-binding protein 1a (SREBP-1a) target genes, we identified and cloned a cDNA… (More)
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Highly Cited
1999
Highly Cited
1999
Arachidonic (20:4(n-6)), eicosapentaenoic (20:5(n-3)), and docosahexaenoic (22:6(n-3)) acids are major components of brain and… (More)
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Review
1993
Review
1993
Linoleic acid is the main dietary essential fatty acid (EFA). To be fully utilized by the body, it must be metabolized to a range… (More)
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Highly Cited
1991
Highly Cited
1991
Stearoyl-acyl-carrier-protein (ACP) desaturase (EC 1.14.99.6) was purified to homogeneity from avocado mesocarp, and monospecific… (More)
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