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lifibrol

Known as: 4-(4'-tert-butylphenyl)-1-(4'-carboxyphenoxy)-2-butanol 
A novel lipid-lowering agent with a complicated mechanism of action. Lifibrol may affect bile acid metabolism, enhance sterol excretion, reduce… Expand
National Institutes of Health

Papers overview

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2004
2004
The efficacy and safety of lifibrol, a novel cholesterol-lowering drug, was investigated in a double-blind clinical study in 168… Expand
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Review
2003
Review
2003
Current lipid-altering agents that lower low density lipoprotein cholesterol (LDL-C) primarily through increased hepatic LDL… Expand
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2000
2000
Three polymorphic modifications of lifibrol, a novel cholesterol-lowering drug substance, were detected and thoroughly… Expand
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2000
2000
Lifibrol (4-(4'-tert. butylphenyl)-1-(4'-carboxyphenoxy)-2-butanol) is a new hypocholesterolemic compound; it effectively lowers… Expand
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2000
2000
Lifibrol (4-(4'-tert-butylphenyl)-1-(4'carboxyphenoxy)-2-butanol) is a new hypocholesterolemic drug effectively reducing total… Expand
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1995
1995
To determine the effects of lifibrol on serum lipids in adult patients with primary hypercholesterolemia. 
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1995
1995
Cytosolic HMG-CoA synthase and microsomal 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase catalyze two sequential steps in the… Expand
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1994
1994
In vitro data suggests that lifibrol lowers plasma cholesterol by inhibiting cholesterol synthesis. We report that lifibrol is… Expand
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1994
1994
Lifibrol, a new drug for the treatment of hypercholesterolemia, contains a stereogenic center bearing a secondary alcohol group… Expand
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1990
1990
We investigated the hypolipidemic property of lifibrol in male and female minipigs in a long term trial over a treatment period… Expand
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