leukotriene biosynthetic process

Known as: leukotriene formation, leukotriene synthesis, leukotriene biosynthesis 
The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated… (More)
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO… (More)
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Review
2005
Review
2005
The anti-inflammatory properties of ginger have been known and valued for centuries. During the past 25 years, many laboratories… (More)
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Highly Cited
2002
Highly Cited
2002
We previously reported the identification of a locus on mouse chromosome 6 that confers almost total resistance to atherogenesis… (More)
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Highly Cited
2002
Highly Cited
2002
Leptin is an adipocyte-derived hormone that is secreted in correlation with total body lipid stores. Serum leptin levels are… (More)
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Highly Cited
1998
Highly Cited
1998
From bronchoprovocation studies and investigations of the acute effects of drugs that inhibit leukotrienes (LT), the hypothesis… (More)
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Highly Cited
1997
Highly Cited
1997
Phospholipase A2 (PLA2) enzymes are critical regulators of prostaglandin and leukotriene synthesis and can directly modify the… (More)
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Highly Cited
1992
Highly Cited
1992
One of the features of inflammation is increased oxygenation of arachidonic acid which is metabolized by two enzymic pathways… (More)
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Highly Cited
1990
Highly Cited
1990
LEUKOTRIENES, the biologically active metabolites of arachidonic acid, have been implicated in a variety of inflammatory… (More)
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Highly Cited
1990
Highly Cited
1990
Recently, we have shown that ionophore activation of human leukocytes results in leukotriene synthesis and a translocation of 5… (More)
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Highly Cited
1989
Highly Cited
1989
The role of leukotrienes in the pathogenesis of chronic colitis was investigated using a rat model. Ulceration and inflammation… (More)
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