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leukotriene A4 hydrolase

Known as: LTA4 hydrolase, leukotriene A4 aminopeptidase 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Epoxide hydrolase
LTA4H gene

Narrower (1)

Leukotriene A-4 Hydrolase, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Investigation of resolvin E1 as a metabolite of eicosapentaenoic acid with anti-colorectal cancer activity
Eicosapentaenoic acid (EPA) is an omega (ω)-3 polyunsaturated fatty acid (PUFA) found at high levels in oily fish such as salmon… 
2015
2015
PENG: A Neural Gas-Based Approach for Pharmacophore Elucidation. Method Design, Validation, and Virtual Screening for Novel Ligands of LTA4H
The pharmacophore concept is commonly employed in virtual screening for hit identification. A pharmacophore is generally defined… 
2015
2015
A via dos leucotrienos contribui para os efeitos antiinflamatórios do treinamento físico aeróbio na asma
Os leucotrienos (LTs) desempenham um papel central na fisiopatologia da asma. O exercicio fisico aerobico tem demonstrado ser… 
2014
2014
HIGH CARBOHYDRATE DIET ENHANCES LEUKOTRIENE A4 HYDROLASE AND EXACERBATES ISOPROTERENOL-INDUCED MYOCARDIAL DAMAGE
Leukotriene A4 hydrolase (LTA4H) catalyzes production of the proinflammatory lipid mediator, leukotriene (LT) B4, which is… 
2013
2013
JJC In Silico Identification of Novel Leukotriene A 4 Hydrolase Inhibitors as Potential Anti-Inflammatory Agents
Leukotriene A4 Hydrolase (LTA4H) is considered an indispensable enzyme in the cascade of producing inflammatory mediators… 
2011
2011
An Efficient Pharmacophore Generation Strategy To Identify New Leukotriene A 4 Hydrolase ( lta 4 h )
  • 2011
  • Corpus ID: 38617874
Leukotriene A4 Hydrolase as a potent inhibitor in inflammation. Leukotriene A4 hydrolase, also known as LTA4H is a human gene… 
1996
1996
The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by leukotriene A4 hydrolase and metallopeptidase inhibitors.
The lethal factor of Bacillus anthracis is central to the pathogenesis of anthrax. Its mechanism of action is still unknown… 
1996
1996
Synthesis of Bestatin, a Potent Inhibitor of Leukotriene A4 Hydrolase, by an N3 Nucleophile Reaction to a Non-protected Diol.
The synthesis of bestatin (1), based on the regio-selective introduction of a nitrogen function to a non-protected diol 9, is… 
1994
1994
Leukotriene A4 hydrolase in human skin.
The biochemical properties and immunohistochemical localization of leukotriene (LT) A4 hydrolase were investigated in human skin… 
1994
1994
Leukotriene A4 hydrolase, a target for inhibition of leukotriene B4 formation in the epidermis in psoriasis
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