leukemia inhibitory factor

Known as: Myeloid Differentiation Stimulating Factor, Inhibitory Factor, Leukemia, Differentiation-Stimulating Factor 
An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2018
05010019622018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Human and mouse embryonic stem cells (ESCs) are derived from blastocyst-stage embryos but have very different biological… (More)
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Highly Cited
2009
Highly Cited
2009
After optic nerve injury retinal ganglion cells (RGCs) normally fail to regenerate axons in the optic nerve and undergo apoptosis… (More)
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Highly Cited
2005
Highly Cited
2005
Murine ES cells can be maintained as a pluripotent, self-renewing population by LIF/STAT3-dependent signaling. The downstream… (More)
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Highly Cited
2000
Highly Cited
2000
The roles that thymus cytokines might play in regulating thymic atrophy are not known. Reversing thymic atrophy is important for… (More)
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Highly Cited
1998
Highly Cited
1998
Leukemia inhibitory factor is essential for embryo implantation, and a shift from type 1 T-helper to type 2 T-helper response at… (More)
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Highly Cited
1998
Highly Cited
1998
The differentiation of precursor cells into neurons or astrocytes in the developing brain has been thought to be regulated in… (More)
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Highly Cited
1996
Highly Cited
1996
Cardiotrophin-1 (CT-1) was recently isolated by expression cloning based on its ability to induce an increase in cell size in… (More)
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Highly Cited
1996
Highly Cited
1996
We previously reported the purification, culture-expansion, and osteogenic differentiation potential of mesenchymal progenitor… (More)
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Highly Cited
1995
Highly Cited
1995
The low-affinity receptor for leukemia inhibitory factor (LIFR) interacts with gp130 to induce an intracellular signal cascade… (More)
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Highly Cited
1994
Highly Cited
1994
We have found that CNTF and LIF are pleiotropic modulators of development in the O-2A lineage. Both molecules enhanced the… (More)
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