leucine metabolic process

Known as: leucine metabolism 
The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid. [GOC:ai]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2018
05101519592018

Papers overview

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Highly Cited
2002
Highly Cited
2002
Acute administration of leucine and norleucine activates the mammalian target of rapamycin (mTOR) cell-signaling pathway and… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Inadequate dietary protein intake results in loss of skeletal muscle mass. Some shorter-term nitrogen balance studies… (More)
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Highly Cited
1996
Highly Cited
1996
Mechanisms of protein gain during protein feeding have been investigated using a combination of oral and intravenous labeled… (More)
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Highly Cited
1990
Highly Cited
1990
This study examined whether variability among healthy young adults in resting metabolic rate, normalized for the amount of… (More)
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Highly Cited
1987
Highly Cited
1987
We examined the effect of insulin and plasma amino acid concentrations on leucine kinetics in 15 healthy volunteers (age 22 +/- 2… (More)
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Highly Cited
1985
Highly Cited
1985
In vivo effects of insulin on plasma leucine and alanine kinetics were determined in healthy postabsorptive young men (n = 5… (More)
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Highly Cited
1985
Highly Cited
1985
To investigate in humans whether interconversion of leucine and its alpha-keto acid, alpha-ketoisocaproate (KIC), is rate… (More)
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Highly Cited
1980
Highly Cited
1980
Leucine metabolism in vivo can be determined from a primed, continuous infusion of L-[1-13C]leucine by measuring, at isotopic… (More)
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Highly Cited
1979
Highly Cited
1979
Glucose and leucine metabolism in 18 severely burned patients were studied using the primed constant infusion of U-13C-glucose… (More)
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Highly Cited
1966
Highly Cited
1966
At present, leucine-induced hypoglycemia and maple-syrup urine disease are the only inborn errors of leucine metabolism… (More)
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