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lecozotan

Known as: 4-Cyano-N-(2R-(4-(2,3-dihydrobenzo(1,4)-dioxin-5-yl)-piperazin-1-yl)-propyl)-N-pyridin-2-yl-benzamide 
 
National Institutes of Health

Papers overview

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2010
2010
Lecozotan is a selective serotonergic 5-HT(1A) receptor antagonist previously shown to enhance task performance efficiency in… Expand
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2009
2009
AIMS To determine the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of oral immediate release (IR) lecozotan in healthy… Expand
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2008
2008
This positron emission tomography (PET) study was conducted to assess binding of lecozotan, a new potent and silent 5… Expand
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2008
2008
There is a potential risk that 5-HT(1A) receptor blockade combined with blockade of the 5-HT transporter by an SSRI may cause a… Expand
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Highly Cited
2005
Highly Cited
2005
Recent data has suggested that the 5-hydroxytryptamine (5-HT)1A receptor is involved in cognitive processing. A novel 5-HT1A… Expand
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2005
2005
A series of benzodioxanylpiperazine derivatives possessing a 4-aryl amide substituent was prepared and evaluated for 5-HT(1A… Expand
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