laulimalide

Known as: fijianolide B 
 

Topic mentions per year

Topic mentions per year

1999-2017
024619992017

Papers overview

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2014
2014
Laulimalide and peloruside A are microtubule-stabilizing agents (MSAs), the mechanism of action on microtubules of which is… (More)
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2010
2010
Conventional approaches to site mapping have so far failed to identify the laulimalide binding site on microtubules. Using mass… (More)
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2006
2006
Some of the most significant therapeutic leads and agents used for the treatment of cancer target microtubule dynamics… (More)
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2006
2006
Previous studies on the drug content of pelleted tubulin polymers suggest that peloruside A binds in the laulimalide site, which… (More)
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2005
2005
Laulimalide is one of the newest naturally occurring macrolides known to act as a microtubule stabilizing agent with properties… (More)
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2004
2004
Microtubule-stabilising agents laulimalide and peloruside have been compared with tubulin-interacting drugs paclitaxel and… (More)
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2004
2004
Laulimalide is a potent, structurally unique microtubule-stabilizing agent originally isolated from the marine sponge Cacospongia… (More)
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Highly Cited
2002
Highly Cited
2002
Laulimalide is a cytotoxic natural product that stabilizes microtubules. The compound enhances tubulin assembly, and laulimalide… (More)
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2001
2001
An enantioselective first total synthesis of laulimalide (1) is described. Laulimalide, a remarkably potent antitumor macrolide… (More)
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Highly Cited
1999
Highly Cited
1999
A mechanism-based screening program aimed at the discovery of new antimicrotubule agents from natural products yielded… (More)
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