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lanosterol 14 alpha-demethylase

Known as: Cytochrome P 450 CYP51, 14alpha-Demethylase, Obtusifoliol, Eburicol 14 alpha Demethylase 
An NADPH-dependent P450 enzyme that plays an essential role in the sterol biosynthetic pathway by catalyzing the demethylation of 14-methyl sterols… 
National Institutes of Health

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CYP51A1 geneIn BloodProcess of secretionaspects of radiation effects

Papers overview

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Review
2011
Review
2011
A review of chromatographic characterization techniques for biodiesel and biodiesel blends.
This review surveys chromatographic technology that has been applied to the characterization of biodiesel and its blends… 
Review
2008
Review
2008
Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections.
Chagas disease is caused by infection with the protozoan pathogen, Trypanosoma cruzi. The only approved therapeutics for treating… 
Highly Cited
2007
Highly Cited
2007
Sterol methenyl transferase inhibitors alter the ultrastructure and function of the Leishmania amazonensis mitochondrion leading to potent growth inhibition.
Highly Cited
2006
Highly Cited
2006
Mechanistic Analysis of a Multiple Product Sterol Methyltransferase Implicated in Ergosterol Biosynthesis in Trypanosoma brucei*
Sterol methyltransferase (SMT) plays a key role in sterol biosynthesis in different pathogenic organisms by setting the pattern… 
Highly Cited
2005
Highly Cited
2005
ANALYSIS OF STERYL GLUCOSIDES IN FOODS AND DIETARY SUPPLEMENTS BY SOLID‐PHASE EXTRACTION AND GAS CHROMATOGRAPHY
A method to quantify b -sitosterol (BSS) and b -sitosteryl glucoside (BSSG) in dietary supplements containing added BSS and BSSG… 
Highly Cited
1999
Highly Cited
1999
Formation of Azole-Resistant Candida albicans by Mutation of Sterol 14-Demethylase P450
ABSTRACT The sterol 14-demethylase P450 (CYP51) of a fluconazole-resistant isolate of Candida albicans, DUMC136, showed reduced… 
Highly Cited
1996
Highly Cited
1996
Isolation and Reconstitution of the Heme-Thiolate Protein Obtusifoliol 14α-Demethylase from Sorghum bicolor (L.) Moench*
The heme-thiolate (cytochrome P450) enzyme which catalyzes the 14α-demethylation of obtusifoliol has been isolated from… 
1994
1994
Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.
The discovery of selective lanosterol 14 alpha-demethylase inhibitors may lead to novel hypolipidemic drugs. RS-21607, (2S,4S… 
Highly Cited
1977
Highly Cited
1977
Influence of dietary vitamin D3 on the circulating concentration of its active metabolites in the chick and rat.
Plasma concentrations of 25-hydroxyvitamin D3 (25-OHD3) and 1 alpha,25-dihydroxyvitamin D3 (1 alpha, 25-(OH)2D3) in growing… 
Highly Cited
1969
Highly Cited
1969
Characteristics of a New Sterol-nonrequiring Mycoplasma
Two Mycoplasma strains recovered from tissue culture environments were found to grow in complex media devoid of serum or serum… 
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