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kynurenine-oxoglutarate aminotransferase activity

Known as: kynurenine--oxoglutarate aminotransferase activity, L-kynurenine aminotransferase activity, kynurenine-oxoglutarate transaminase activity 
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate. [EC:2.6.1.7]
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
OBJECTIVE This study characterized the kynurenine pathway (KP) in human obesity by evaluating circulating levels of kynurenines… Expand
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2014
2014
BACKGROUND Cognitive deficits compromise quality of life and productivity for individuals with schizophrenia and have no… Expand
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Highly Cited
2012
Highly Cited
2012
Increased inflammation and reduced neurogenesis have been associated with the pathophysiology of major depression. Here, we show… Expand
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Highly Cited
2011
Highly Cited
2011
CONTEXT Kynurenic acid, a metabolite of the kynurenine pathway of tryptophan degradation, is an antagonist at N-methyl-d… Expand
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2009
2009
In contrast to the wide spectrum of cytochrome P450 monooxygenases, there are only 2 heme-based dioxygenases in humans… Expand
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2009
2009
Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) are heme enzymes that catalyze the O(2)-dependent… Expand
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Highly Cited
2007
Highly Cited
2007
In contrast to the diverse superfamily of monooxygenases, there are only two classes of heme-containing dioxygenases in humans… Expand
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Highly Cited
2002
Highly Cited
2002
The use of eye-color mutants and their corresponding genes as scorable marker systems has facilitated the development of… Expand
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2001
2001
As part of an ongoing search to identify novel mammalian photopigments that may mediate nonvisual tasks such as circadian… Expand
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1970
1970
1. The ability of tricarboxylic acid-cycle metabolites to influence the physiological performance of the perfused anaerobic rat… Expand
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