kynurenine-oxoglutarate aminotransferase activity

Known as: kynurenine--oxoglutarate aminotransferase activity, L-kynurenine aminotransferase activity, kynurenine-oxoglutarate transaminase activity 
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate. [EC:2.6.1.7]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1961-2016
012319612016

Papers overview

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2017
2017
Kynurenine monooxygenase (KMO) is a potential drug target for treatment of neurodegenerative disorders such as Huntington's and… (More)
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2015
2015
Cognitive dysfunction in depression is a prevalent and debilitating symptom that is poorly treated by the currently available… (More)
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2014
2014
For analysis of nitration modification of α oxoglutarate dehydrogenase (α-OGDH) induced by diabetes, a targeted proteomics… (More)
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2009
2009
Although oxidative stress induces mitochondrial DNA (mtDNA) damage, a role for redox in modulating mtDNA oxidation and repair is… (More)
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2004
2004
BACKGROUND The activity of nicotinic acid in hypercholesterolemia has been poorly understood. In man, nicotinic acid derives for… (More)
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2003
2003
In some animals, the administration of repeated doses of tryptophan can cause death. It has been reported that guinea pig does… (More)
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1987
1987
The reduction of cytochrome c was found in the presence of N-formyl-L-kynurenine (NFK) and L-kynurenine (KN) during irradiation… (More)
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1982
1982
The effects of gamma-aminobutyric acid (GABA)-alpha-oxoglutarate aminotransferase (GABA-T) inhibitors, L-glutamic acid… (More)
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1975
1975
Glutamine, in the presence of alpha-oxoglutarate, stimulates nicotinamide nucleotide oxidation by crude extracts of pea roots and… (More)
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1961
1961
1. Evidence is presented for the presence of pyridoxamine phosphate oxidase and a pyridoxal phosphate phosphatase in aqueous… (More)
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