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kynurenic acid biosynthetic process

Known as: 4-hydroxyquinoline-2-carboxylic acid biosynthetic process, kynurenic acid biosynthesis, kynurenic acid anabolism 
The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid. [CHEBI:18344, GOC:mah]
National Institutes of Health

Papers overview

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2015
2015
The tryptophan metabolite, kynurenic acid (KYNA), is a preferential antagonist of the α7 nicotinic acetylcholine receptor at… Expand
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2012
2012
BACKGROUND Patients with schizophrenia show increased brain and cerebrospinal fluid (CSF) concentrations of the endogenous N… Expand
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2010
2010
Fluctuations in the brain levels of the neuromodulator kynurenic acid may control cognitive processes and play a causative role… Expand
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Review
2008
Review
2008
Kynurenine aminotransferases are pyridoxal-5'-phosphate-dependent enzymes, which catalyze the synthesis of kynurenic acid, a… Expand
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2004
2004
Summary.Kynurenic acid (KYNA), an endogenous glutamate-receptor antagonist preferentially blocking NMDA-receptors, has analgesic… Expand
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2002
2002
Studies with brain slices have provided evidence that synthesis of kynurenic acid (KYNA) from kynurenine (KYN), which occurs in… Expand
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Review
1999
Review
1999
  • Flavio Moroni
  • European journal of pharmacology
  • 1999
  • Corpus ID: 4554610
The synthesis of NAD (or NADP) from tryptophan involves a series of enzymes and the formation of a number of intermediates which… Expand
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1998
1998
This study was designed to investigate the role of cellular energy metabolism in the de novo formation of the endogenous… Expand
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1997
1997
This study was designed to investigate modulatory mechanisms that control the synthesis of the neuroprotective endogenous… Expand
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1992
1992
The present study was designed to examine the cellular localization and biosynthetic machinery of the broad-spectrum excitatory… Expand
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