kynurenic acid biosynthetic process

Known as: 4-hydroxyquinoline-2-carboxylic acid biosynthetic process, kynurenic acid biosynthesis, kynurenic acid anabolism 
The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid. [CHEBI:18344, GOC:mah]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
01219922017

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2017
2017
Cognitive deficits represent core symptoms in schizophrenia (SZ) and predict patient outcome; however, they remain poorly treated… (More)
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2015
2015
In respect to the functional activities of D-cycloserine scientists suggested anticonvulsive activities [4,5] and furthermore the… (More)
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2012
2012
BACKGROUND Patients with schizophrenia show increased brain and cerebrospinal fluid (CSF) concentrations of the endogenous N… (More)
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2006
2006
The synthesis of the NMDA receptor glycine site antagonist kynurenic acid (KYNA) from exogenously added kynurenine was measured… (More)
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2004
2004
Kynurenic acid (KYNA), an endogenous glutamate-receptor antagonist preferentially blocking NMDA-receptors, has analgesic… (More)
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2002
2002
Studies with brain slices have provided evidence that synthesis of kynurenic acid (KYNA) from kynurenine (KYN), which occurs in… (More)
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1998
1998
This study was designed to investigate the role of cellular energy metabolism in the de novo formation of the endogenous… (More)
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1997
1997
This study was designed to investigate modulatory mechanisms that control the synthesis of the neuroprotective endogenous… (More)
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1996
1996
Kynurenic acid is an endogenous, competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor glycine site. Accordingly… (More)
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1992
1992
The production of the broad spectrum excitatory amino acid receptor antagonist kynurenic acid was assessed by hippocampal… (More)
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