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ko2 mu-urea-phe-hphe vinylsulfone

Known as: morpholine-urea-phe-homo-phe-vinylsulfone, mu-urea-phe-hphe vinylsulfone 
 
National Institutes of Health

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2 relations

Broader (2)

DipeptidesMorpholines

Papers overview

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2013
2013
Chemical–biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target
Summary Inhibition of the Trypanosoma cruzi cysteine protease cruzain has been proposed as a therapeutic approach for the… Expand
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2007
2007
Highly Potent and Selective Substrate Analogue Factor Xa Inhibitors Containing D‐Homophenylalanine Analogues as P3 Residue: Part 2
A series of highly potent substrate‐analogue factor Xa inhibitors containing D‐homophenylalanine analogues as the P3 residue has… Expand
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2007
2007
Rehabilitation inpatients are not meeting their energy and protein needs
Summary Background & aims This study aimed to determine the amounts of energy and protein required, ordered and consumed daily by… Expand
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Highly Cited
2006
Highly Cited
2006
Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease.
In this study we investigated why bloodstream forms of Trypanosoma brucei gambiense cross human brain microvascular endothelial… Expand
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Highly Cited
2005
Highly Cited
2005
Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants
Diseases of specific fibrocartilaginous joints are especially common in women of reproductive age, suggesting that female… Expand
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Highly Cited
1999
Highly Cited
1999
Designing an intervention to prevent suicide: PROSPECT (Prevention of Suicide in Primary Care Elderly: Collaborative Trial)
Suicide is a major public health problem with greatest risk in the very old. This paper describes an approach to reducing the… Expand
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Highly Cited
1998
Highly Cited
1998
The Eating Inventory in obese women: Clinical correlates and relationship to weight loss
OBJECTIVES: Describe the physical and psychological correlates of the Eating Inventory (EI) (also known as the Three-Factor… Expand
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Highly Cited
1998
Highly Cited
1998
Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A.
We evaluated delta-9 tetrahydrocannabinol (Delta9-THC), delta-8 tetrahydrocannabinol (Delta8-THC), CP55,940 (CP55), 1-deoxy-11… Expand
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Highly Cited
1998
Highly Cited
1998
Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor.
K02 (morpholine-urea-Phe-Hphe-vinylsulfone), a newly developed peptidomimetic, acts as a potent cysteine protease inhibitor… Expand
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Highly Cited
1997
Highly Cited
1997
Wheels, wheeling, and the Kontsevich integral of the Unknot
We conjecture an exact formula for the Kontsevich integral of the unknot, and also conjecture a formula (also conjectured… Expand
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