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kinetochore assembly

Known as: centromere and kinetochore complex maturation, centromere/kinetochore complex maturation, kinetochore biogenesis 
The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The kinetochore forms a dynamic interface with microtubules from the mitotic spindle during mitosis. The Ndc80 complex acts as… Expand
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Highly Cited
2011
Highly Cited
2011
Accurate chromosome segregation requires assembly of the multiprotein kinetochore complex at centromeres. Although prior work… Expand
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Highly Cited
2011
Highly Cited
2011
During cell division, chromosomes are segregated to nascent daughter cells by attaching to the microtubules of the mitotic… Expand
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Highly Cited
2011
Highly Cited
2011
Centromeres provide a region of chromatin upon which kinetochores are assembled in mitosis. Centromeric protein C (CENP-C) is a… Expand
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Highly Cited
2010
Highly Cited
2010
The NSL1 subunit structures interactions between the MIS12, NDC80, and KNL1 kinetochore complexes (see also a related paper by… Expand
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Highly Cited
2006
Highly Cited
2006
The centromere-specific histone variant CENP-A (CID in Drosophila) is a structural and functional foundation for kinetochore… Expand
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Highly Cited
2003
Highly Cited
2003
Kinetochores are multiprotein complexes that assemble on centromeric DNA and attach chromosomes to spindle microtubules. Over the… Expand
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Highly Cited
2003
Highly Cited
2003
We show that the Xenopus homologs of Ndc80/Tid3/HEC1 (xNdc80) and Nuf2/MPP1/Him-10 (xNuf2) proteins physically interact in a 190… Expand
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Highly Cited
2001
Highly Cited
2001
In all eukaryotes, segregation of mitotic chromosomes requires their interaction with spindle microtubules. To dissect this… Expand
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Highly Cited
1999
Highly Cited
1999
We have identified SGT1 as a dosage suppressor of skp1-4, a mutation causing defects in yeast kinetochore function. Sgt1p… Expand
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