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kinase inhibitor activity

Known as: kinase inhibitor 
Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate… 
National Institutes of Health

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Kinase Inhibitors [MoA]kinase activitykinase inhibitorkinase inhibitor [EPC]

Papers overview

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2014
2014
Protective effect of Rho kinase inhibitor on brain tissue of rat with chronic hypoperfusion injury
Objective To explore protective effect of Rho kinase inhibitor on brain tissue of rat with chronic hypoperfusion injury. Methods… 
2012
2012
Protective effects of Rho kinase inhibitor on rats’ vascular endothelium and its effects on the expression of eNO
Objective 　To explore the protective effects of Rho kinase inhibitor (fasudil) on rats' vascular endothelial cells and the… 
2008
2008
Fasudil (a rho-kinase inhibitor) may specifically increase rCBF in spastic area
Pathophysiological mechanisms underlying vasospasm are diverse and not yet fully elucidated. However, it has recently been shown… 
2008
2008
Effects of Rho kinase inhibitor on myocardial hypertrophy induced by isoproterenol in rats
Objective To investigate the effects of Rho kinase inhibitor on myocardial hypertrophy induced by isoproterenol (Iso) in rats and… 
2005
2005
Gene transfer of a β2-adrenergic receptor kinase inhibitor up-regulates the level of β2-adrenergic receptor and cAMP in the asthmatic murine lung
Objective: To investigate the effects of gene transfer of a β-adrenergic receptor(β-AR) kinase inhibitor(β ARKct)on pulmonary β2… 
2004
2004
Rho kinase inhibitor Y-27632 prevents partially burn serum-induced endothelial barrier dysfunction
AIM: To investigate whether small GTPase RhoA's downstream effector Rho kinase mediates burn serum-induced endothelial… 
2001
2001
High Affinity Binding of the Heat-stable Protein Kinase Inhibitor to the Catalytic Subunit of CAMP-dependent Protein Kinase Is Selectively Abolished by Mutation of Arg 133*
The two classes of physiological inhibitors of the cata- lytic subunit of CAMP-dependent protein kinase are the regulatory… 
2001
2001
Novel and specific Rho-kinase inhibitor, H1152P, directed against the Rho-kinase involved pathway
1977
1977
Regulation of protein kinase by vasopressin in renal medulla in situ.
Results of this study demonstrate that vasopressin activates protein kinase in intact renal medullary cells as detected by… 
1976
1976
Regulation of protein kinase in rat pineal: increased Vmax in supersensitive glands.
Protein kinase activity was examined in supernatants from super-sensitive and subsensitive rat pineal glands both in the presence…