Skip to search formSkip to main contentSkip to account menu

isopropyl unoprostone

Known as: Isopropyl (+)-( Z )-7-[(1 R, 2 R, 3 R, 5 S )-3,5-dihydroxy-2-(3-oxodecyl) Cyclopentyl]-5-heptenoate, Unoprostone Isopropyl, isopropyl 20-ethyl-9alpha,11alpha-dihydroxy-15-keto-cis-delta-5-prostanoate 
A docosanoid and a structural analogue of an inactive biosynthetic cyclic derivative of arachidonic acid, 13,14-dihydro-15-keto-prostaglandin F 2a… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (2)

Antihypertensive AgentsDinoprost
Drug AllergyGlaucoma, Open-AngleProstaglandinsanalogs & derivatives

Narrower (2)

EesculaUF 021

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Prostaglandin analogues and mouse intraocular pressure: effects of tafluprost, latanoprost, travoprost, and unoprostone, considering 24-hour variation.
PURPOSE To establish a mouse model for the pharmacological analysis of antiglaucoma drugs, considering the effect of variations… 
2002
2002
Comparison between isopropyl unoprostone and latanoprost by prostaglandin E(2)induction, affinity to prostaglandin transporter, and intraocular metabolism.
The pharmacological differences between isopropyl unoprostone (referred to as unoprostone) and latanoprost, concerning their… 
2002
2002
A Comparative Clinical Study of Latanoprost and Isopropyl Unoprostone in Japanese Patients with Primary Open-Angle Glaucoma and Ocular Hypertension
PurposeTo compare the efficacy and safety of latanoprost versus isopropyl unoprostone (unoprostone) in Japanese patients with… 
2001
2001
Isopropyl Unoprostone Increases the Activities of Matrix Metalloproteinases in Cultured Monkey Ciliary Muscle Cells
PurposeThe mechanism by which the prostaglandin F 2&agr; -related antiglaucoma compound isopropyl unoprostone (referred to as… 
2001
2001
Photoreceptor Protection against Constant Light-Induced Damage by Isopropyl Unoprostone, a Prostaglandin F2α Metabolite-Related Compound
Some of the antiglaucoma drugs have shown neuroprotective effects in ischemic retinal damage and optic nerve injury. We studied… 
2001
2001
A Comparison of Intraocular Pressure-Lowering Effect of Prostaglandin F2-&agr; Analogues, Latanoprost, and Unoprostone Isopropyl
PurposeTo compare the intraocular pressure-lowering effect of unoprostone isopropyl (unoprostone) 0.12% and latanoprost 0.005%. A… 
2001
2001
An evaluation of the effect of unoprostone isopropyl 0.15% on ocular hemodynamics in normal-tension glaucoma patients
Abstract. Background: Because intraocular pressure-lowering agents should have a good safety profile with regard to ocular… 
1999
1999
Metabolites of isopropyl unoprostone as potential ophthalmic solutions to reduce intraocular pressure in pigmented rabbits.
The intraocular metabolism of isopropyl unoprostone, a novel prostaglandin-related anti-glaucoma compound, was investigated using… 
Highly Cited
1998
Highly Cited
1998
A comparative study of latanoprost (Xalatan) and isopropyl unoprostone (Rescula) in normal and glaucomatous monkey eyes.
1998
1998
The Effects of Unoprostone Isopropyl 0.12% and Timolol Maleate 0.5% on Diurnal Intraocular Pressure
PurposeTo compare the effect of unoprostone isopropyl 0.12% to that of timolol maleate 0.5% solution given twice daily on the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)