isopenicillin N synthetase

In a chemically defined medium with glucose and sucrose as major carbon sources (standard medium), Cephalosporium acremonium… (More)

A transformation system for Ophiostoma ulmi (Buism.) Nannf. was developed and analyzed. Protoplasts were generated from actively… (More)

The alpha-aminoadipoyl group of the natural substrate of isopenicillin N synthetase (IPNS), L-alpha-aminoadipoyl-L-cysteinyl-D… (More)

Total RNA was extracted daily from the β-lactam antibiotic producing fungus A. chrysogenum strain CO728 during a 7 day… (More)

Clones of Aspergillus nidulans genomic DNA spanning 20 kb have been isolated and shown by a combination of classical and… (More)

A cosmid clone containing the putative penicillin biosynthetic gene cluster from Penicillium chrysogenum was used to transform… (More)

Isopenicillin N synthetase (IPNS) from Acremonium chrysogenum was photolabelled by laser-flash photolysis in the presence of a… (More)

Isopenicillin N synthetase was purified from Streptomyces clavuligerus by sequential salt precipitation, ion-exchange and gel… (More)

The levels of three enzymes of the β-lactam antibiotic pathway and overall cephalosporin production were subject to nitrogen… (More)

Isopenicillin N synthetase was extracted from Cephalosporium acremonium and purified about 200-fold. The product showed one major… (More)